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Characteristics and outcomes of COVID-19 patients admitted to hospital with and without respiratory symptoms
dc.contributor.author | Citarella B.W | |
dc.contributor.author | Kartsonaki C | |
dc.contributor.author | Ibáñez-Prada E.D | |
dc.contributor.author | Gonçalves B.P | |
dc.contributor.author | Baruch J | |
dc.contributor.author | Escher M | |
dc.contributor.author | Pritchard M.G | |
dc.contributor.author | Wei J | |
dc.contributor.author | Philippy F | |
dc.contributor.author | Dagens A | |
dc.contributor.author | Hall M | |
dc.contributor.author | Lee J | |
dc.contributor.author | Kutsogiannis D.J | |
dc.contributor.author | Wils E.-J | |
dc.contributor.author | Fernandes M.A | |
dc.contributor.author | Tirupakuzhi Vijayaraghavan B.K | |
dc.contributor.author | Panda P.K | |
dc.contributor.author | Martin-Loeches I | |
dc.contributor.author | Ohshimo S. | |
dc.date.accessioned | 2024-10-09T14:28:40Z | |
dc.date.available | 2024-10-09T14:28:40Z | |
dc.date.issued | 2024 | |
dc.identifier.issn | 24058440 | |
dc.identifier.other | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85192803986&doi=10.1016%2fj.heliyon.2024.e29591&partnerID=40&md5=0a6201e55b55f604d094960b5889386f | |
dc.identifier.uri | http://hdl.handle.net/10818/61983 | |
dc.description.abstract | Background: COVID-19 is primarily known as a respiratory illness; however, many patients present to hospital without respiratory symptoms. The association between non-respiratory presentations of COVID-19 and outcomes remains unclear. We investigated risk factors and clinical outcomes in patients with no respiratory symptoms (NRS) and respiratory symptoms (RS) at hospital admission. Methods: This study describes clinical features, physiological parameters, and outcomes of hospitalised COVID-19 patients, stratified by the presence or absence of respiratory symptoms at hospital admission. RS patients had one or more of: cough, shortness of breath, sore throat, runny nose or wheezing; while NRS patients did not. Results: Of 178,640 patients in the study, 86.4 % presented with RS, while 13.6 % had NRS. NRS patients were older (median age: NRS: 74 vs RS: 65) and less likely to be admitted to the ICU (NRS: 36.7 % vs RS: 37.5 %). NRS patients had a higher crude in-hospital case-fatality ratio (NRS 41.1 % vs. RS 32.0 %), but a lower risk of death after adjusting for confounders (HR 0.88 [0.83–0.93]). Conclusion: Approximately one in seven COVID-19 patients presented at hospital admission without respiratory symptoms. These patients were older, had lower ICU admission rates, and had a lower risk of in-hospital mortality after adjusting for confounders. © 2024 The Authors | en |
dc.format | application/pdf | es_CO |
dc.language.iso | eng | es_CO |
dc.publisher | Heliyon | es_CO |
dc.relation.ispartofseries | Heliyon Vol. 10 N° 10 art. e29591 | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.source | Universidad de La Sabana | es_CO |
dc.source | Intellectum Repositorio Universidad de La Sabana | es_CO |
dc.subject.other | COVID-19 | en |
dc.subject.other | Mortality | en |
dc.subject.other | Non-respiratory symptoms | en |
dc.subject.other | Respiratory symptoms | en |
dc.subject.other | Risk factors | en |
dc.title | Characteristics and outcomes of COVID-19 patients admitted to hospital with and without respiratory symptoms | en |
dc.type | journal article | es_CO |
dc.type.hasVersion | publishedVersion | es_CO |
dc.rights.accessRights | openAccess | es_CO |
dc.identifier.doi | 10.1016/j.heliyon.2024.e29591 |
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Facultad de Medicina [1043]