Apresentar o registro simples

dc.contributor.authorCuestas D
dc.contributor.authorGómez A
dc.contributor.authorNeri Morales C
dc.contributor.authorMotta A
dc.contributor.authorRolon M
dc.contributor.authorSuarez S
dc.contributor.authorPolo R.
dc.date.accessioned2024-10-07T21:39:23Z
dc.date.available2024-10-07T21:39:23Z
dc.date.issued2024
dc.identifier.issn3403696
dc.identifier.otherhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85198345825&doi=10.1007%2fs00403-024-03016-x&partnerID=40&md5=ff24dcca65fce1442bc48e96e7333d22
dc.identifier.urihttp://hdl.handle.net/10818/61899
dc.description.abstractCongenital epidermodysplasia verruciformis (CEV) is a Genodermatosis linked to different inheritance patterns and mutations of the EVER1/TMC6 and EVER2/TMC8 genes. There is an acquired form (AEV) associated with immunodeficiency states, including human immunodeficiency virus (HIV) infection; however, the literature about AEV is limited and imprecise, so a systematic review was performed. A search of the main databases from 1975 to 2021 identified 126 studies, of which 80 met the inclusion criteria. The diagnosis of AEV is complex due to atypical manifestations and locations, it requires a mean follow-up of 7 years, and the lesions do not change with ART therapy, CD4 count, or viral load. Histopathological findings are variable depending on the location of the lesions. HPV 5 remains the serotype most frequently associated with AEV and CEV, although HPV 20 is more frequent than HPV 8 in AEV. Most treatments have low efficacy, the most described are glycolic acid 15%, 5-fluorouracil 5%, imiquimod 5%, and topical retinoids all of them in monotherapy or combined with cryotherapy. Other alternatives include topical cidofovir and systemic retinoids with variable results. The oncologic prognosis is still inconclusive; however, the development of squamous cell carcinoma and melanoma are frankly lower concerning CEV. This review opens new opportunities for future research. Additionally, we provide clear and useful key points for the practice of dermatologists and all professionals treating HIV patients around the world. © The Author(s) 2024.en
dc.formatapplication/pdfes_CO
dc.language.isoenges_CO
dc.publisherArchives of Dermatological Researches_CO
dc.relation.ispartofseriesArchives of Dermatological Research Vol. 316 N° 7 art. 471
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.sourceUniversidad de La Sabanaes_CO
dc.sourceIntellectum Repositorio Universidad de La Sabanaes_CO
dc.subject.otherEpidermodysplasia verruciformisen
dc.subject.otherHIVen
dc.subject.otherHPVen
dc.subject.otherSkin canceren
dc.titleAcquired epidermodysplasia verruciformis syndrome in HIV-infected patients: a systematic reviewen
dc.typejournal articlees_CO
dc.type.hasVersionpublishedVersiones_CO
dc.rights.accessRightsopenAccesses_CO
dc.identifier.doi10.1007/s00403-024-03016-x


Arquivos deste item

ArquivosTamanhoFormatoVisualização

Não existem arquivos associados a este item.

Este item aparece na(s) seguinte(s) coleção(s)

Apresentar o registro simples

Attribution-NonCommercial-NoDerivatives 4.0 InternationalExceto quando indicado o contrário, a licença deste item é descrito como Attribution-NonCommercial-NoDerivatives 4.0 International