dc.contributor.author | García-Silva J | |
dc.contributor.author | Ulloa-Gutierrez R | |
dc.contributor.author | Ivankovich-Escoto G | |
dc.contributor.author | Yamazaki-Nakashimada M.A | |
dc.contributor.author | Faugier-Fuentes E | |
dc.contributor.author | del Águila O | |
dc.contributor.author | Camacho-Moreno G | |
dc.contributor.author | Estripeaut D | |
dc.contributor.author | Gutiérrez I.F | |
dc.contributor.author | Castillo-Bustamante D | |
dc.contributor.author | Luciani K | |
dc.contributor.author | Fabi M | |
dc.contributor.author | Espada G | |
dc.contributor.author | Álvarez-Olmos M.I | |
dc.contributor.author | Silfa C | |
dc.contributor.author | Pérez-Camacho P | |
dc.contributor.author | Duarte-Passos S | |
dc.contributor.author | Cervi M.C | |
dc.contributor.author | Martínez-Ramírez R.O | |
dc.contributor.author | Cantillano E.M | |
dc.contributor.author | Llamas-Guillén B.A | |
dc.contributor.author | Velásquez-Méndez M | |
dc.contributor.author | Saltigeral-Simental P | |
dc.contributor.author | Criales J | |
dc.contributor.author | Fernández-Sarmiento J | |
dc.contributor.author | Chacon-Cruz E | |
dc.contributor.author | García-Domínguez M | |
dc.contributor.author | Aguilar K.L.B | |
dc.contributor.author | Villarreal-Treviño A.V | |
dc.contributor.author | Tremoulet A.H. | |
dc.date.accessioned | 2024-10-07T21:39:21Z | |
dc.date.available | 2024-10-07T21:39:21Z | |
dc.date.issued | 2024 | |
dc.identifier.issn | 27727076 | |
dc.identifier.other | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85203086490&doi=10.1016%2fj.ijregi.2024.100419&partnerID=40&md5=1017f58d7287f64d24e25c1eb95caf67 | |
dc.identifier.uri | http://hdl.handle.net/10818/61895 | |
dc.description.abstract | Objectives: Our aim was to describe the epidemiology and outcomes of multisystem inflammatory syndrome in children (MIS-C) in Latin America. Methods: We conducted an observational, retrospective, and prospective multicenter study that gathered information from 84 participating centers across 16 Latin American countries between August 1, 2020 and June 30, 2022. Results: Of the 1239 reported children with MIS-C, 84.18% were previously healthy. The most frequent clinical manifestation in our studied population was abdominal pain (N = 804, 64.9%), followed by conjunctival injection (N = 784, 63.3%). The median duration of fever at the time of hospital admission was 5 days and a significant number of subjects required admission to an intensive care unit (N = 589, 47.5%). Most of the subjects (N = 1096, 88.7%) were treated with intravenous immunoglobulin, whereas 76.7% (N = 947) were treated with steroids, of whom 10.6% (N = 100) did not receive intravenous immunoglobulin. The death rate attributed to MIS-C was 4.88%, with a rate of 3.39% for those initially diagnosed with MIS-C and 8.85% for those whose admission diagnosis was not MIS-C (P <0.001, odds ratio 2.76, 95% confidence interval 1.6-4.6). Conclusions: One of the most significant findings from our study was the death rate, especially in those not initially diagnosed with MIS-C, in whom the rate was higher. This highlights the importance of increasing awareness and making an earlier diagnosis of MIS-C in Latin America. © 2024 The Author(s) | en |
dc.format | application/pdf | es_CO |
dc.language.iso | eng | es_CO |
dc.publisher | IJID Regions | es_CO |
dc.relation.ispartofseries | IJID Regions Vol. 12 N° art. 100419 | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.source | Universidad de La Sabana | es_CO |
dc.source | Intellectum Repositorio Universidad de La Sabana | es_CO |
dc.subject.other | Latin America | en |
dc.subject.other | Multisystem Inflammatory Syndrome in Children (MIS-C) | en |
dc.title | Multisystem inflammatory syndrome in children across 16 Latin American countries: A multicenter study from the REKAMLATINA Network | en |
dc.type | journal article | es_CO |
dc.type.hasVersion | publishedVersion | es_CO |
dc.rights.accessRights | openAccess | es_CO |
dc.identifier.doi | 10.1016/j.ijregi.2024.100419 | |