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dc.contributor.authorGiraldo Cadavid, Luis Fernando
dc.contributor.authorInsignares, Diego
dc.contributor.authorVelasco, Valentina
dc.contributor.authorLondoño, Natalia
dc.contributor.authorGalvis, Ana María
dc.contributor.authorRengifo, María Leonor
dc.contributor.authorBastidas, Alirio R.
dc.date.accessioned2024-01-12T20:18:58Z
dc.date.available2024-01-12T20:18:58Z
dc.date.issued2023-08-08
dc.identifier.urihttp://hdl.handle.net/10818/59050
dc.description20 páginases_CO
dc.description.abstractBackground: Aspiration detected in the fiberoptic endoscopy evaluation of swallowing (FEES) has been inconsistently associated with pneumonia, with no evidence of the risk of pneumonia from other alterations in swallowing safety detected in FEES. Methods: We performed a dynamic, ambidirectional cohort study of 148 subjects at risk of dysphagia in a tertiary university hospital to determine the risk of pneumonia due to alterations in the swallowing safety of FEES. We used multivariate negative binomial regression models to adjust for potential confounders. Results: The incidence density rate (IR) of pneumonia in patients with tracheal aspiration of any consistency was 26.6/100 people-years (RR 7.25; 95% CI: 3.50 to 14.98; P < 0.001). The IR was 19.7/100 people-years (RR 7.85; 95% CI: 3.34 to 18.47; P < 0.001) in those with laryngeal penetration of any consistency and 18.1/100 people-years (RR 6.24; 95% CI: 2.58 to 15.09; P < 0.001) in those with pharyngeal residue of any consistency. When adjusted for aspiration, the association of residue and penetration with pneumonia disappeared, suggesting that their risk of pneumonia is dependent on the presence of aspiration and that only aspiration is independently associated with pneumonia. This increased risk of pneumonia was significant in uni- and multivariate negative binomial regression models. Conclusions: We found an independently increased risk of pneumonia in the presence of aspiration in FEES. Alterations in the oral and pharyngeal phases of swallowing, without aspiration, did not increase the risk of pneumonia.es_CO
dc.formatapplication/pdfes_CO
dc.language.isoenges_CO
dc.publisherUniversidad de La Sabanaes_CO
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.titleFiberoptic Endoscopy Evaluation of Swallowing (FEES) Findings Associated with High Pneumonia Risk in a Cohort of Patients at Risk of Dysphagiaes_CO
dc.typemaster thesises_CO
dc.type.hasVersionpublishedVersiones_CO
dc.rights.accessRightsrestrictedAccesses_CO
dc.subject.decsDeglutition
dc.subject.decsDeglutition disorders
dc.subject.decsRespiratory aspiration
dc.subject.decsPneumonia
thesis.degree.disciplineFacultad de Medicinaes_CO
thesis.degree.levelMaestría en Epidemiologíaes_CO
thesis.degree.nameMagíster en Epidemiologíaes_CO


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Attribution-NonCommercial-NoDerivatives 4.0 InternacionalExcept where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 Internacional