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Administration and therapeutic drug monitoring of β-lactams 2 and vancomycin in critical care units in Colombia : The ANTI- 3 BIOCOL study
dc.contributor.advisor | Díaz Quijano, Diana Marcela | |
dc.contributor.author | Fuentes Barreiro, Yuly Viviana | |
dc.contributor.other | Blanco Mejía, Jhosep Andrés | |
dc.contributor.other | Lechtig, Sharon | |
dc.contributor.other | Liebisch Rey, Hans Nicolás | |
dc.contributor.other | Díaz Pinilla, Nicolás | |
dc.contributor.other | Vergara Ramírez, Peter | |
dc.contributor.other | Bustos Cruz, Rosa Helena | |
dc.date.accessioned | 2022-01-27T14:47:40Z | |
dc.date.available | 2022-01-27T14:47:40Z | |
dc.date.issued | 2021-08-11 | |
dc.identifier.uri | http://hdl.handle.net/10818/49519 | |
dc.description | 15 páginas | es_CO |
dc.description.abstract | Therapeutic Drug Monitoring (TDM) and continuous infusion strategies are effec- 15 tive interventions in clinical practice, but these practices are little still unknown in Colombia, 16 especially in the critical care setting. This study aims to describe the practices of administra- 17 tion and TDM of time-dependent antibiotics reported by specialists in critical care in Colom- 18 bia and to explore the factors that are related to the use of extended infusion. An online na- 19 tionwide survey was applied to 153 specialists selected randomly. A descriptive, bivariate 20 analysis and a logistic regression model were performed. Of the 88.9% of intensivists referred 21 to TDM availability, 21.57% has access to results access in less than 6 hours. TDM was avail- 22 able mainly for vancomycin. 85.62% of the intensivists had some type of institutional proto- 23 col, however, only 39.22% had a complete and socialized protocol. The odds of preferring 24 extended infusions among those who do not have institutional protocols decrease by 80% 25 compared with those with complete protocols, OR 0.2 (95% CI: 0.06 - 0.61). The most im- 26 portant perceived barriers to performing continuous infusions and TDM are the lack of train- 27 ing and technologies. This pioneering study in Colombia could impact the quality of care and 28 outcomes of critically ill patients on the threat that is antimicrobial resistance. | en |
dc.format | application/pdf | es_CO |
dc.language.iso | eng | es_CO |
dc.publisher | Universidad de La Sabana | es_CO |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.source | Universidad de La Sabana | |
dc.source | Intellectum Repositorio Universidad de La Sabana | |
dc.title | Administration and therapeutic drug monitoring of β-lactams 2 and vancomycin in critical care units in Colombia : The ANTI- 3 BIOCOL study | en |
dc.type | master thesis | es_CO |
dc.identifier.local | 283024 | |
dc.identifier.local | TE11429 | |
dc.type.hasVersion | publishedVersion | es_CO |
dc.rights.accessRights | restrictedAccess | es_CO |
dc.subject.armarc | Farmacovigilancia | es_CO |
dc.subject.armarc | Cuidados intensivos | es_CO |
dc.subject.armarc | Encuestas de salud | es_CO |
dc.subject.decs | Agentes antiinfecciosos | es_CO |
dc.subject.decs | Vancomicina | es_CO |
thesis.degree.discipline | Facultad de Medicina | es_CO |
thesis.degree.level | Maestría en Epidemiología | es_CO |
thesis.degree.name | Magíster en Epidemiología | es_CO |