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dc.contributor.authorRomero Sánchez, C.
dc.contributor.authorBautista Molano, W.
dc.contributor.authorParra, V.
dc.contributor.authorAvila, J. De
dc.contributor.authorRueda, J. C.
dc.contributor.authorBello Gualtero, J. M.
dc.contributor.authorLondoño Patiño, John Darío
dc.contributor.authorValle Oñate, R. 11:43
dc.description9 páginases_CO
dc.description.abstractBackground. Spondyloarthritis (SpA) is a group of articular inflammatory rheumatic diseases that their gastrointestinal manifestations are around 10% of their extra-articular symptoms, supporting that the inflammatory response of the intestinal mucosa could be associated with the clinical status. Objectives. To investigate the association between gastrointestinal symptoms and autoantibodies and disease activity between SpA patients, healthy subjects (HS), and patients with inflammatory bowel disease (IBD). Methods. 102 SpA patients, 29 IBD patients, and 117 HS were included. Autoantibodies as ASCA, ANCA, anti-tTG, anti-DGP, ANA, and IgA were measured. The patients were assessed to evaluate clinical and gastrointestinal symptoms. An association analysis was performed using Chi square test and a logistic regression. Results. Significant differences were found for ASCA levels in SpA (28.2%) compared to IBD (14.2%) and HS (6.0%) (), as well as for ANAS in SpA (49.5%) and IBD (37.9%) () and abdominal pain () between SpA (54.3%) and IBD (27.5%). Significant associations were found between BASDAI > 4 and gastrointestinal symptoms () and IgA (). The association for abdominal bloating was maintained (OR: 3.93, CI-95%, 1.14–13.56; ). Conclusions. Gastrointestinal symptoms, ASCA, ANAS, and IgA levels were associated with high disease activity in SpA compared with IBD and HS.en
dc.publisherInternational Journal of Rheumatology
dc.publisherInternational Journal of Rheumatologyes_CO
dc.relation.ispartofseriesInt J Rheumatol . 2017;2017:4029584
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.sourceUniversidad de La Sabanaes_CO
dc.sourceIntellectum Repositorio Universidad de La Sabanaes_CO
dc.subjectAnti-Saccharomyces cerevisiaees_CO
dc.titleGastrointestinal Symptoms and Elevated Levels of Anti- Saccharomyces cerevisiae Antibodies Are Associated with Higher Disease Activity in Colombian Patients with Spondyloarthritises_CO

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Attribution-NonCommercial-NoDerivatives 4.0 InternationalExcept where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 International