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Alzheimer: Una mirada neurofisiológica y patológica de la enfermedad. ¿Dónde se origina la enfermedad?

dc.contributor.advisorSuárez Baquero, Alejandra
dc.contributor.authorRugeles Castañeda, Andrea
dc.date.accessioned2012-05-15T19:16:46Z
dc.date.available2012-05-15T19:16:46Z
dc.date.created2007
dc.date.issued2012-05-15
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dc.identifier.urihttp://hdl.handle.net/10818/2168
dc.description44 Páginas.
dc.description.abstractEl Alzheimer es una enfermedad degenerativa progresiva del cerebro, se manifiesta por la desorientación y perdida de memoria. Fue descrita en 1906, por Alois Alzheimer. Anatomopatológicamente, se caracteriza por la aparición de placas seniles conformadas por la acumulación de la molécula amieloide, producto de la APP. Están implicados los cromosomas 1, 14, 19 y 21. El cromosoma 19, sintetiza la proteína activadora APOE, responsable del inicio de la enfermedad. Se han evidenciado anomalías inmunológicas debido a que la molécula amieloide no suele encontrarse en los vertebrados, por lo tanto éstos carecen de enzimas necesarias para degradarla; ello podría explicar la progresiva acumulación de amieloide; motivo por el cual las células de la microglía se activan pero no responden inmunológicamente.es_CO
dc.language.isoeses_CO
dc.publisherUniversidad de La Sabana
dc.sourceUniversidad de la Sabana
dc.sourceIntellectum Repositorio Universidad de la Sabana
dc.subjectEnfermedad de Alzheimeres_CO
dc.subjectEnfermedades del sistema nerviosoes_CO
dc.titleAlzheimer: Una mirada neurofisiológica y patológica de la enfermedad. ¿Dónde se origina la enfermedad?es_CO
dc.typebachelorThesis
dc.publisher.programPsicología
dc.publisher.departmentFacultad de Psicología
dc.identifier.local88334
dc.identifier.localTE04585
dc.type.localTesis de pregrado
dc.type.hasVersionpublishedVersion
dc.rights.accessRightsopenAccess
dc.creator.degreePsicólogo


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