Minute ventilation in cardiorespiratory exercise and its relationship with ventricular ejection fraction
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URI: http://hdl.handle.net/10818/63289Visitar enlace: https://www.scopus.com/inward/ ...
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Bastidas-Goyes A.; Tuta-Quintero E.; Botero J.D.; Rosas D.B.; Prieto D.; Rubio D.; López C.; Hincapie G.A.; Mantilla B.; Brito A.; Vargas T.; Forero S.; Villarraga L.; Giraldo A.; Briceño M.; Porras A.Date
2024Abstract
Introduction: Cardiorespiratory exercise testing is a non-invasive alternative in the assessment of subjects with heart failure. Objective: To evaluate the validity of ventilatory equivalents for carbon dioxide (VE/VCO2) as a predictor of left ventricular ejection fraction (LVEF) compared to peak oxygen consumption. Methods: Cross-sectional analytical study in patients undergoing cardiopulmonary exercise testing and transthoracic echocardiography. The study was divided into a group with reduced LVEF < 40% and preserved ≥ 40%. Bivariate analysis comparing qualitative variables with the chi-square test and quantitative variables with Student's t-test was performed. A Receiver Operating Characteristic (ROC) curve was constructed to evaluate the discriminatory capacity between ventilatory equivalent for carbon dioxide and peak oxygen pulse. Results: The final analysis included 138 patients. In patients with reduced LVEF, peak oxygen consumption averaged 1.6 L/min (SD ± 0.68) compared to 1.7 L/min (SD ± 0.66) in the control group (p= 0.513). VE/VCO2 during ventilatory threshold and peak exercise averaged 38.4 (SD ± 7.38) and 44.6 (SD ± 8.24), respectively. The discriminatory performance of VE/VCO2 versus peak oxygen consumption was 0.737 (95% CI: 0.596-0.878; p= 0.008) in patients with reduced LVEF. Conclusions: VE/VCO2 is a reliable predictor of normal or reduced LVEF and performs well compared to peak oxygen consumption. © 2024, Editorial Ciencias Medicas. All rights reserved.
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Revista Cubana de Medicina Militar vol. 53 n. 3
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