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Encapsulation of high oleic palm oil using microfluidization and electrospinning: physicochemical characterization and nanotoxicity performance
dc.contributor.advisor | Quintanilla Carvajal, María Ximena | |
dc.contributor.author | Ricaurte Puentes, Leidy Yineth | |
dc.date.accessioned | 2020-12-17T17:02:02Z | |
dc.date.available | 2020-12-17T17:02:02Z | |
dc.date.issued | 2020-10-11 | |
dc.identifier.uri | http://hdl.handle.net/10818/45995 | |
dc.description | 198 páginas | es_CO |
dc.description.abstract | Colombia is one of the leaders of palm oil production with 540,688 hectares harvested in 2019 (Fedepalma, 2019b), and a yield of 3.8 oil tons per hectare achieved in 2017 (overcoming the world average). Despite this, only 42% was sold to produce biodiesel and the 0.1% for oil and fat industry (Fedepalma, 2019a), contributing in a 9% to the gross domestic product (PIB, according to its Spanish abbreviation) of the country in 2018 (Fedepalma, 2018). The palm oil is an edible vegetable oil, which is extracted from mesocarp of several palm species with an orange-red color due to the presence of carotenoids (Marangoni et al., 2015). Currently a hybrid between Elaeis Guinensis and Oleifera has been widely harvested which produces an oil with high concentration of oleic acid (55%) compared to 41% from traditional palm oil (Mozzon et al., 2013). Therefore, it is known as high oleic palm oil (HOPO). The HOPO has showed to be ‘the tropical oil equivalent of olive oil’ due to several authors have reported similar effect on plasma lipids, for this oil and extra virgin olive oil (Lucci et al., 2016). Likewise, the antioxidant capacity of human plasma increased significantly after 3 months of supplementation with HOPO (Ojeda et al., 2017). For this reason, using this oil in final edible products could enhance the quality of nutrition in Colombia, for its high concentrations of vitamin E, beta-carotene, and high unsaturated fatty acids that could be supplied. However, those labile compounds are typically lost during food processing. Hence, to assure a high concentration not only in the product, but also after the intake, encapsulation has been proposed as protection technique. | en |
dc.format | application/pdf | es_CO |
dc.language.iso | eng | es_CO |
dc.publisher | Universidad de La Sabana | es_CO |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.source | Universidad de La Sabana | |
dc.source | Intellectum Repositorio Universidad de La Sabana | |
dc.title | Encapsulation of high oleic palm oil using microfluidization and electrospinning: physicochemical characterization and nanotoxicity performance | en |
dc.type | doctoral thesis | es_CO |
dc.identifier.local | 279968 | |
dc.identifier.local | TE11049 | |
dc.type.hasVersion | publishedVersion | es_CO |
dc.rights.accessRights | restrictedAccess | es_CO |
dc.subject.armarc | Encapsulación | spa |
dc.subject.armarc | Aceite de palma | spa |
dc.subject.armarc | Nanotecnología | spa |
dcterms.references | Abdel-Khalek, A. A., Kadry, M. A. M., Badran, S. R., & Marie, M.-A. S. (2015). Comparative toxicity of copper oxide bulk and nano particles in Nile Tilapia; Oreochromis niloticus: Biochemical and oxidative stress. The Journal of Basic & Applied Zoology, 72, 43–57. https://doi.org/https://doi.org/10.1016/j.jobaz.2015.04.001 | eng |
dcterms.references | Arora, S., Rajwade, J. M., & Paknikar, K. M. (2012). Nanotoxicology and in vitro studies: The need of the hour. Toxicology and Applied Pharmacology, 258(2), 151–165. https://doi.org/10.1016/j.taap.2011.11.010 | eng |
dcterms.references | Bala, K., Ambwani, K., & Gohil, N. K. (2011). Effect of different mitogens and serum concentration on HUVEC morphology and characteristics: Implication on use of higher passage cells. Tissue and Cell, 43(4), 216–222. https://doi.org/https://doi.org/10.1016/j.tice.2011.03.004 | eng |
dcterms.references | Bazana, M. T., Codevilla, C. F., & de Menezes, C. R. (2019). Nanoencapsulation of bioactive compounds: challenges and perspectives. Current Opinion in Food Science, 26, 47–56. https://doi.org/https://doi.org/10.1016/j.cofs.2019.03.005 | eng |
dcterms.references | Cao, Y., Gong, Y., Liu, L., Zhou, Y., Fang, X., Zhang, C., Li, Y., & Li, J. (2017). The use of human umbilical vein endothelial cells (HUVECs) as an in vitro model to assess the toxicity of nanoparticles to endothelium: a review. Journal of Applied Toxicology, 37(12), 1359–1369. https://doi.org/10.1002/jat.3470 | eng |
dcterms.references | Cardona, M., López, J. A., Serafín, A., Rongvaux, A., Inserte, J., García-Dorado, D., Flavell, R., Llovera, M., Cañas, X., Vázquez, J., & Sanchis, D. (2015). Executioner Caspase-3 and 7 Deficiency Reduces Myocyte Number in the Developing Mouse Heart. PloS One, 10(6), e0131411–e0131411. https://doi.org/10.1371/journal.pone.0131411 | eng |
dcterms.references | Chen, W., Ju, X., Aluko, R. E., Zou, Y., Wang, Z., Liu, M., & He, R. (2020). Rice bran protein-based nanoemulsion carrier for improving stability and bioavailability of quercetin. Food Hydrocolloids, 108, 106042. https://doi.org/https://doi.org/10.1016/j.foodhyd.2020.106042 | eng |
dcterms.references | Cook-Johnson, R. J., Demasi, M., Cleland, L. G., Gamble, J. R., Saint, D. A., & James, M. J. (2006). Endothelial cell COX-2 expression and activity in hypoxia. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1761(12), 1443–1449. https://doi.org/https://doi.org/10.1016/j.bbalip.2006.09.003 | eng |
dcterms.references | Farshi, P., Tabibiazar, M., Ghorbani, M., Mohammadifar, M., Amirkhiz, M. B., & Hamishehkar, H. (2019). Whey protein isolate-guar gum stabilized cumin seed oil nanoemulsion. Food Bioscience, 28, 49–56. https://doi.org/https://doi.org/10.1016/j.fbio.2019.01.011 | eng |
dcterms.references | Genah, S., Angeli, A., Supuran, C. T., & Morbidelli, L. (2020). Effect of Carbonic Anhydrase IX inhibitors on human endothelial cell survival. Pharmacological Research, 159(May), 104964. https://doi.org/10.1016/j.phrs.2020.104964 | eng |
dcterms.references | Golebiowski, B., Chao, C., Bui, K. A., Lam, W. Y. W., Richdale, K., & Stapleton, F. (2020). Effect of age and contact lens wear on corneal epithelial dendritic cell distribution, density, and morphology. Contact Lens and Anterior Eye, 43(1), 84–90. https://doi.org/https://doi.org/10.1016/j.clae.2019.05.002 | eng |
dcterms.references | İnal, M., & Mülazımoğlu, G. (2019). Production and characterization of bactericidal wound dressing material based on gelatin nanofiber. International Journal of Biological Macromolecules, 137, 392–404. https://doi.org/10.1016/j.ijbiomac.2019.06.119 | eng |
dcterms.references | Iyer, V. R., Eisen, M. B., Ross, D. T., Schuler, G., Moore, T., Lee, J. C. F., Trent, J. M., Staudt, L. M., Jr, J. H., Boguski, M. S., Lashkari, D., Shalon, D., Botstein, D., & Brown, P. O. (1999). The Transcriptional Program in the response of fibroblast. Science, 283, 83–87. | eng |
dcterms.references | Ji, X., Usman, A., Razalli, N. H., Sambanthamurthi, R., & Gupta, S. V. (2015). Oil Palm Phenolics (OPP) Inhibit Pancreatic Cancer Cell Proliferation via Suppression of NF- κB Pathway. Anticancer Research, 106, 97–106. | eng |
dcterms.references | Kaur, K., Kumar, R., Arpita, Goel, S., Uppal, S., Bhatia, A., & Mehta, S. K. (2017). Physiochemical and cytotoxicity study of TPGS stabilized nanoemulsion designed by ultrasonication method. Ultrasonics Sonochemistry, 34, 173–182. https://doi.org/https://doi.org/10.1016/j.ultsonch.2016.05.037 | eng |
dcterms.references | Kent, K. D., Harper, W. J., & Bomser, J. A. (2003). Effect of whey protein isolate on intracellular glutathione and oxidant-induced cell death in human prostate epithelial cells. Toxicology in Vitro, 17(1), 27–33. https://doi.org/10.1016/S0887-2333(02)00119-4 | eng |
dcterms.references | Lippens, S., Kockx, M., Knaapen, M., Mortier, L., Polakowska, R., Verheyen, A., Garmyn, M., Zwijsen, A., Formstecher, P., Huylebroeck, D., Vandenabeele, P., & Declercq, W. (2000). Epidermal differentiation does not involve the pro-apoptotic executioner caspases, but is associated with caspase-14 induction and processing. Cell Death & Differentiation, 7(12), 1218–1224. https://doi.org/10.1038/sj.cdd.4400785 | eng |
dcterms.references | Lucci, P., Borrero, M., Ruiz, A., Pacetti, D., Frega, N. G., Diez, O., Ojeda, M., Gagliardi, R., Parra, L., & Angel, M. (2016). Palm oil and cardiovascular disease: A randomized trial of the effects of hybrid palm oil supplementation on human plasma lipid patterns. Food and Function, 7(1), 347–354. https://doi.org/10.1039/c5fo01083g | eng |
dcterms.references | Manders, E. M. M., Verbeek, F. J., & Aten, J. A. (1993). Measurement of co‐localization of objects in dual‐ colour confocal images. Journal of Microscopy, 169(3), 375–382. https://doi.org/10.1111/j.1365- 2818.1993.tb03313.x | eng |
dcterms.references | Manzuoerh, R., Farahpour, M. R., Oryan, A., & Sonboli, A. (2019). Effectiveness of topical administration of Anethum graveolens essential oil on MRSA-infected wounds. Biomedicine & Pharmacotherapy, 109, 1650–1658. https://doi.org/https://doi.org/10.1016/j.biopha.2018.10.117 | eng |
dcterms.references | McClements, D. J., & Rao, J. (2011). Food-Grade nanoemulsions: Formulation, fabrication, properties, performance, Biological fate, and Potential Toxicity. Critical Reviews in Food Science and Nutrition, 51(4), 285–330. https://doi.org/10.1080/10408398.2011.559558 | eng |
dcterms.references | McIlwain, D. R., Berger, T., & Mak, T. W. (2015). Caspase functions in cell death and disease. Cold Spring Harbor Perspectives in Biology, 7(4). https://doi.org/10.1101/cshperspect.a026716 | eng |
dcterms.references | Mehrabadi, M. E., Salemi, Z., Babaie, S., & Panahi, M. (2018). Effect of Biochanin A on Retina Levels of Vascular Endothelial Growth Factor, Tumor Necrosis Factor-Alpha and Interleukin-1Beta in Rats With Streptozotocin-Induced Diabetes. Canadian Journal of Diabetes, 42(6), 639–644. https://doi.org/https://doi.org/10.1016/j.jcjd.2018.03.008 | eng |
dcterms.references | Miura, M., Chen, X.-D., Allen, M. R., Bi, Y., Gronthos, S., Seo, B.-M., Lakhani, S., Flavell, R. A., Feng, X.-H., Robey, P. G., Young, M., & Shi, S. (2004). A crucial role of caspase-3 in osteogenic differentiation of bone marrow stromal stem cells. The Journal of Clinical Investigation, 114(12), 1704–1713. https://doi.org/10.1172/JCI20427 | eng |
dcterms.references | Mozzon, M., Pacetti, D., Lucci, P., Balzano, M., & Frega, N. G. (2013). Crude palm oil from interspecific hybrid Elaeis oleifera × Elaeis guineensis: Fatty acid regiodistribution and molecular species of glycerides. Food Chemistry, 141(1), 245–252. https://doi.org/10.1016/j.foodchem.2013.03.016 | eng |
dcterms.references | Mutalib, M. S. A., Khaza’ai, H., & Wahle, K. W. J. (2003). Palm-tocotrienol rich fraction (TRF) is a more effective inhibitor of LDL oxidation and endothelial cell lipid peroxidation than α-tocopherol in vitro. Food Research International, 36(5), 405–413. https://doi.org/10.1016/S0963-9969(02)00173-4 | eng |
dcterms.references | Nitta, Y., Muraoka-Hirayama, S., & Sakurai, K. (2020). Catalase is required for peroxisome maintenance during adipogenesis. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1865(8), 158726. https://doi.org/https://doi.org/10.1016/j.bbalip.2020.158726 | eng |
dcterms.references | Pérez-Garijo, A. (2018). When dying is not the end: Apoptotic caspases as drivers of proliferation. Seminars in Cell & Developmental Biology, 82, 86–95. https://doi.org/https://doi.org/10.1016/j.semcdb.2017.11.036 | eng |
dcterms.references | Petersen, S., Steiniger, F., Fischer, D., Fahr, A., & Bunjes, H. (2011). The physical state of lipid nanoparticles influences their effect on in vitro cell viability. European Journal of Pharmaceutics and Biopharmaceutics, 79(1), 150–161. https://doi.org/https://doi.org/10.1016/j.ejpb.2011.03.022 | eng |
dcterms.references | Pisoschi, A. M., Pop, A., Cimpeanu, C., Turcuş, V., Predoi, G., & Iordache, F. (2018). Nanoencapsulation techniques for compounds and products with antioxidant and antimicrobial activity - A critical view. European Journal of Medicinal Chemistry, 157, 1326–1345. https://doi.org/https://doi.org/10.1016/j.ejmech.2018.08.076 | eng |
dcterms.references | Pyrshev, K. A., Yesylevskyy, S. O., Mély, Y., Demchenko, A. P., & Klymchenko, A. S. (2017). Caspase3 activation decreases lipid order in the outer plasma membrane leaflet during apoptosis: A fluorescent probe study. Biochimica et Biophysica Acta (BBA) - Biomembranes, 1859(10), 2123–2132. https://doi.org/https://doi.org/10.1016/j.bbamem.2017.08.002 | eng |
dcterms.references | Ricaurte, L., Hernández-Carrión, M., Moyano-Molano, M., Clavijo-Romero, A., & Quintanilla-Carvajal, M. X. (2018). Physical, thermal and thermodynamical study of high oleic palm oil nanoemulsions. Food Chemistry, 256(February), 62–70. https://doi.org/10.1016/j.foodchem.2018.02.102 | eng |
dcterms.references | Ricaurte, L., Perea-Flores, M. de J., Martinez, A., & Quintanilla-Carvajal, M. X. (2016). Production of high-oleic palm oil nanoemulsions by high-shear homogenization (microfluidization) [JOUR]. Innovative Food Science & Emerging Technologies, 35, 75–85. https://doi.org/http://dx.doi.org/10.1016/j.ifset.2016.04.004 | eng |
dcterms.references | Ricaurte, L., & Quintanilla-Carvajal, M. X. (2019). Use of electrospinning technique to produce nanofibres for food industries: A perspective from regulations to characterisations. Trends in Food Science and Technology, 85, 92–106. https://doi.org/S0924224418303315 | eng |
dcterms.references | Ricaurte, L., Santagapita, P. R., Díaz, L. E., & Quintanilla-Carvajal, M. X. (2020). Edible gelatin-based nanofibres loaded with oil encapsulating high-oleic palm oil emulsions. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 595(March), 124673. https://doi.org/10.1016/j.colsurfa.2020.124673 | eng |
dcterms.references | Ricaurte, L., Tello-Camacho, E., & Quintanilla-Carvajal, M. X. (2019). Hydrolysed Gelatin-Derived, Solvent-Free, Electrospun Nanofibres for Edible Applications: Physical, Chemical and Thermal Behaviour. Food Biophysics. https://doi.org/10.1007/s11483-019-09608-9 | eng |
dcterms.references | Rincón, S. M., Hormaza, P. A., Moreno, L. P., Prada, F., Portillo, D. J., García, J. A., & Romero, H. M. (2013). Use of phenological stages of the fruits and physicochemical characteristics of the oil to determine the optimal harvest time of oil palm interspecific OxG hybrid fruits. Industrial Crops and Products, 49, 204–210. https://doi.org/10.1016/j.indcrop.2013.04.035 | eng |
dcterms.references | Rohman, A., Windarsih, A., Erwanto, Y., & Zakaria, Z. (2020). Review on analytical methods for analysis of porcine gelatine in food and pharmaceutical products for halal authentication. Trends in Food Science & Technology, 101, 122–132. https://doi.org/https://doi.org/10.1016/j.tifs.2020.05.008 | eng |
dcterms.references | Rosa, A., Rescigno, A., Piras, A., Atzeri, A., Scano, P., Porcedda, S., Zucca, P., & Assunta Dessì, M. (2012). Chemical composition and effect on intestinal Caco-2 cell viability and lipid profile of fixed oil from Cynomorium coccineum L. Food and Chemical Toxicology, 50(10), 3799–3807. https://doi.org/https://doi.org/10.1016/j.fct.2012.07.003 | eng |
dcterms.references | Shanmugapriya, K., Kim, H., Saravana, P. S., Chun, B.-S., & Kang, H. W. (2018). Astaxanthin-alpha tocopherol nanoemulsion formulation by emulsification methods: Investigation on anticancer, wound healing, and antibacterial effects. Colloids and Surfaces B: Biointerfaces, 172, 170–179. https://doi.org/https://doi.org/10.1016/j.colsurfb.2018.08.042 | eng |
dcterms.references | Shatrova, A. N., Lyublinskaya, O. G., Borodkina, A. V., & Burova, E. B. (2016). Oxidative stress response of human fibroblasts and endometrial mesenchymal stem cells. Cell and Tissue Biology, 10(1), 18–28. https://doi.org/10.1134/S1990519X16010090 | eng |
dcterms.references | Shi, F., Wang, Y.-C., Zhao, T.-Z., Zhang, S., Du, T.-Y., Yang, C.-B., Li, Y.-H., & Sun, X.-Q. (2012). Effects of Simulated Microgravity on Human Umbilical Vein Endothelial Cell Angiogenesis and Role of the PI3K-Akt-eNOS Signal Pathway. PLOS ONE, 7(7), e40365. https://doi.org/10.1371/journal.pone.0040365 | eng |
dcterms.references | Tölle, M., Klöckl, L., Wiedon, A., Zidek, W., van der Giet, M., & Schuchardt, M. (2016). Regulation of endothelial nitric oxide synthase activation in endothelial cells by S1P1 and S1P3. Biochemical and Biophysical Research Communications, 476(4), 627–634. https://doi.org/10.1016/j.bbrc.2016.06.009 | eng |
dcterms.references | Vij, P., & Hardej, D. (2012). Evaluation of tellurium toxicity in transformed and non-transformed human colon cells. Environmental Toxicology and Pharmacology, 34(3), 768–782. https://doi.org/https://doi.org/10.1016/j.etap.2012.09.009 | eng |
dcterms.references | Wen, T., Yang, A., Piao, L., Hao, S., Du, L., Meng, J., Liu, J., & Xu, H. (2019). Comparative study of in vitro effects of different nanoparticles at non-cytotoxic concentration on the adherens junction of human vascular endothelial cells. International Journal of Nanomedicine, 14, 4475–4489. https://doi.org/10.2147/IJN.S208225 | eng |
dcterms.references | Yan, X.-X., Najbauer, J., Woo, C. C., Dashtipour, K., Ribak, C. E., & Leon, M. (2001). Expression of active caspase-3 in mitotic and postmitotic cells of the rat forebrain. Journal of Comparative Neurology, 433(1), 4–22. https://doi.org/10.1002/cne.1121 | eng |
dcterms.references | Yap, H.-M., & Lye, K.-L. (2020). An Insight of Vitamin E as Neuroprotective Agents. Progress In Microbes & Molecular Biology, 3(1), 1–6. https://doi.org/10.36877/pmmb.a0000071 | eng |
dcterms.references | Yap, H.-M., & Lye, K.-L. (2020). An Insight of Vitamin E as Neuroprotective Agents. Progress In Microbes & Molecular Biology, 3(1), 1–6. https://doi.org/10.36877/pmmb.a0000071 | eng |
dcterms.references | Yoon, B. H., Lee, S. M., Chang, H.-I., & Ha, C. H. (2019). Mannoproteins from Saccharomyces cerevisiae stimulate angiogenesis by promoting the akt-eNOS signaling pathway in endothelial cells. Biochemical and Biophysical Research Communications, 519(4), 767–772. https://doi.org/https://doi.org/10.1016/j.bbrc.2019.09.069 | eng |
dcterms.references | Yosefzon, Y., Soteriou, D., Feldman, A., Kostic, L., Koren, E., Brown, S., Ankawa, R., Sedov, E., Glaser, F., & Fuchs, Y. (2018). Caspase-3 Regulates YAP-Dependent Cell Proliferation and Organ Size. Molecular Cell, 70(4), 573-587.e4. https://doi.org/https://doi.org/10.1016/j.molcel.2018.04.019 | eng |
dcterms.references | Zaichik, S., Steinbring, C., Jelkmann, M., & Bernkop-Schnürch, A. (2020). Zeta potential changing nanoemulsions: Impact of PEG-corona on phosphate cleavage. International Journal of Pharmaceutics, 581, 119299. https://doi.org/https://doi.org/10.1016/j.ijpharm.2020.119299 | eng |
thesis.degree.discipline | Facultad de Ingeniería | es_CO |
thesis.degree.level | Doctorado en Biociencias | es_CO |
thesis.degree.name | Doctor en Biociencias | es_CO |