Prior influenza vaccine is not a risk of factor for bacterial coinfection in patients admitted to the icu due to severe influenza

Abstract

Influenza vaccination is the most effective strategy to prevent influenza infection worldwide. Moreover, it can also reduce risk of pneumonia and death due to influenza. Thus, current clinical guidelines recommend annual flu vaccination in healthy individuals. However, recent evidence has shown that influenza vaccines might increases upper respiratory tract bacterial colonization and therefore, there may be an increased risk for bacterial co-infection during influenza disease. However, this has not been tested in realworld evidence.