dc.contributor.advisor | Botero Rosas, Daniel Alfonso | |
dc.contributor.author | León Ariza, Henry Humberto | |
dc.date.accessioned | 11/16/2017 10:22 | |
dc.date.available | 11/16/2017 10:22 | |
dc.date.issued | 2017-11-16 | |
dc.identifier.uri | http://hdl.handle.net/10818/31980 | |
dc.description | 211 páginas | es_CO |
dc.description.abstract | El sistema nervioso autónomo (SNA) es responsable entre otras de la regulación inmediata de las funciones vitales, este recibe información constante que se genera tanto interna como externamente, generando respuestas adaptativas inmediatas. Uno de los órganos blanco del SNA es el corazón, el cual modula de manera constante el tiempo entre un latido y otro, haciendo que el estudio de estas variaciones sea un excelente marcador de actividad autonómica. La evidencia sugiere que un estímulo aferente fundamental para la modulación del SNA está en la actividad del sistema inmune, a través de una comunicación mediada por citoquinas. Esta tesis encontró que el sistema inmune efectivamente tiene un impacto en las respuestas del SNA, el cual es explicado por medio de una relación matemática. Para llegar a esta conclusión se cumplieron cinco etapas: 1. Se reprodujo el análisis matemático de la variabilidad de la frecuencia cardiaca desarrollando modelos propios de evaluación. 2. Se determinó la influencia de la composición corporal en el SNA, encontrándose que el tejido adiposo se asocia a una mayor actividad simpática y menor de tipo parasimpático, mientras que la masa muscular se asocia a mayores respuestas parasimpáticas y menores simpáticas, esto especialmente en hombres. 3. Se encontró que la concentración plasmática de marcadores inflamatorios como la Interleucina 6 (IL-6) y especialmente su factor soluble (sIL6R) tienen una alta relación con las respuestas del SNA. 4. Se estableció la influencia que tiene la actividad corteza cerebral en la modulación de las respuestas del SNA. 5. Se generó un modelo matemático que demostró que la IL-6 y el sIL6R son responsables del 50% de los cambios de la actividad autonómica en reposo. | es_CO |
dc.format | application/pdf | es_CO |
dc.language.iso | spa | es_CO |
dc.publisher | Universidad de La Sabana | es_CO |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.source | Universidad de La Sabana | |
dc.source | Intellectum Repositorio Universidad de La Sabana | |
dc.subject | Sistema nervioso autónomo | es_CO |
dc.subject | Frecuencia cardíaca | es_CO |
dc.subject | Sistema inmune | es_CO |
dc.title | Desarrollo de un modelo matemático para establecer la relación fisiológica entre inflamación y sistema nervioso autónomo | es_CO |
dc.type | doctoral thesis | es_CO |
dc.identifier.local | 267052 | |
dc.identifier.local | TE09375 | |
dc.type.hasVersion | publishedVersion | es_CO |
dc.rights.accessRights | openAccess | es_CO |
dcterms.references | Tresguerres JAF, Ariznavarreta C, Cachofeiro V, Cardinati D, Escrich E, Gil-Loyzaga P, et al. Fisiología Humana. Cuarta ed. 2010. } | en |
dcterms.references | Reyes-Juarez JL, Zarain-Herzberg A. Función del retículo sarcoplásmico y su papel en las enfermedades cardíacas. Arch Cardiol Méx 2006;76(suppl 4):18-32. | en |
dcterms.references | Maclennan DH, Kranias EG. Phospholamban: a crucial regulator of cardiac contractility. Nat Rev Mol Cell Biol 2003 Jul;4(7):566-77. | en |
dcterms.references | Chandler N, Aslanidi O, Buckley D, Inada S, Birchall S, Atkinson A, et al. Computer three-dimensional anatomical reconstruction of the human sinus node and a novel paranodal area. Anat Rec (Hoboken ) 2011 Jun;294(6):970-9. | en |
dcterms.references | James TN. The internodal pathways of the human heart. Prog Cardiovasc Dis 2001 May;43(6):495-535. | en |
dcterms.references | Kurian T, Ambrosi C, Hucker W, Fedorov VV, Efimov IR. Anatomy and electrophysiology of the human AV node. Pacing Clin Electrophysiol 2010 Jun 1;33(6):754-62. | en |
dcterms.references | de Micheli SA, Iturralde TP, Aranda FA. About the specialized myocardial conducting tissue. Arch Cardiol Mex 2013 Oct;83(4):278-81. | en |
dcterms.references | Boron WF, Boulpaep EL. Medical Physiology. Segunda ed. Elsevier; 2009. | en |
dcterms.references | Monfredi O, Dobrzynski H, Mondal T, Boyett MR, Morris GM. The anatomy and physiology of the sinoatrial node--a contemporary review. Pacing Clin Electrophysiol 2010 Nov;33(11):1392-406. | en |
dcterms.references | Leon-Ariza HH, Valenzuela-Faccini N, Rojas-Ortega AC, Botero-Rosas DA. Nav1.5 cardiac sodium channels, regulation and clinical implications. Rev Fac Med 2014;62(4):587-92. | en |
dcterms.references | Gordan R, Gwathmey JK, Xie LH. Autonomic and endocrine control of cardiovascular function. World J Cardiol 2015 Apr 26;7(4):204-14. | en |
dcterms.references | Purves D. Neurociencia. Quinta ed. Médica Panamericana; 2016. | en |
dcterms.references | Mohrman DE, Heller LJ. Cardiovascular Physiology. Seventh ed. McGraw-Hill; 2010. | en |
dcterms.references | Venkatakrishnan AJ, Deupi X, Lebon G, Tate CG, Schertler GF, Babu MM. Molecular signatures of G-protein-coupled receptors. Nature 2013 Feb 14;494(7436):185-94 | en |
dcterms.references | Alberts B, Johnson A, Lewis J, Morgan D, Raff M, Roberts K, et al. Molecular Biology of The Cell. Sixth ed. New York: Garland Science; 2015. | en |
dcterms.references | Alberts B, Johnson A, Lewis J, Morgan D, Raff M, Roberts K, et al. Molecular Biology of The Cell. Sixth ed. New York: Garland Science; 2015. | en |
dcterms.references | Mighiu AS, Heximer SP. Controlling Parasympathetic Regulation of Heart Rate: A Gatekeeper Role for RGS Proteins in the Sinoatrial Node. Front Physiol 2012;3:204. | en |
dcterms.references | Larsson HP. How is the heart rate regulated in the sinoatrial node? Another piece to the puzzle. J Gen Physiol 2010 Sep;136(3):237-41. | en |
dcterms.references | Vaseghi M, Shivkumar K. The role of the autonomic nervous system in sudden cardiac death. Prog Cardiovasc Dis 2008 May;50(6):404-19. | en |
dcterms.references | Valente M, De SC, de Martino RP, Di M, V, Di MS, De LT. The direct effect of the thyroid hormone on cardiac chronotropism. Arch Int Physiol Biochim 1989 Dec;97(6):431-40. | en |
dcterms.references | Johnson BD, Zheng W, Korach KS, Scheuer T, Catterall WA, Rubanyi GM. Increased expression of the cardiac L-type calcium channel in estrogen receptordeficient mice. J Gen Physiol 1997 Aug;110(2):135-40. | en |
dcterms.references | Er F, Gassanov N, Brandt MC, Madershahian N, Hoppe UC. Impact of dihydrotestosterone on L-type calcium channels in human ventricular cardiomyocytes. Endocr Res 2009;34(3):59-67. | en |
dcterms.references | Mesirca P, Torrente AG, Mangoni ME. Functional role of voltage gated Ca(2+) channels in heart automaticity. Front Physiol 2015;6:19. | en |
dcterms.references | Gerritsen J, Dekker JM, TenVoorde BJ, Kostense PJ, Heine RJ, Bouter LM, et al. Impaired autonomic function is associated with increased mortality, especially in subjects with diabetes, hypertension, or a history of cardiovascular disease: the Hoorn Study. Diabetes Care 2001 Oct;24(10):1793-8. | en |
dcterms.references | HOLTER NJ. New method for heart studies. Science 1961 Oct 20;134(3486):1214-20. | en |
dcterms.references | Kumagai H, Oshima N, Matsuura T, Iigaya K, Imai M, Onimaru H, et al. Importance of rostral ventrolateral medulla neurons in determining efferent sympathetic nerve activity and blood pressure. Hypertens Res 2012 Feb;35(2):132-41. | en |
dcterms.references | Albaghdadi M. Baroreflex control of long-term arterial pressure . Rev Bras Hipertens 2007;14(4):212-25. | en |
dcterms.references | Crystal GJ, Salem MR. The Bainbridge and the "reverse" Bainbridge reflexes: history, physiology, and clinical relevance. Anesth Analg 2012 Mar;114(3):520-32. | en |
dcterms.references | Swenne CA. Baroreflex sensitivity: mechanisms and measurement. Neth Heart J 2013 Feb;21(2):58-60. | en |
dcterms.references | Andrade DC, Lucero C, Toledo C, Madrid C, Marcus NJ, Schultz HD, et al. Relevance of the Carotid Body Chemoreflex in the Progression of Heart Failure. BioMed Research International 2015;2015(Article ID 467597):1-8. | en |
dcterms.references | Moreira TS, Takakura AC, Damasceno RS, Falquetto B, Totola LT, Sobrinho CR, et
al. Central chemoreceptors and neural mechanisms of cardiorespiratory control.
Braz J Med Biol Res 2011 Sep;44(9):883-9. | en |
dcterms.references | Yasuma F, Hayano J. Respiratory sinus arrhythmia: why does the heartbeat
synchronize with respiratory rhythm? Chest 2004 Feb;125(2):683-90. | en |
dcterms.references | Gladwell VF, Fletcher J, Patel N, Elvidge LJ, Lloyd D, Chowdhary S, et al. The
influence of small fibre muscle mechanoreceptors on the cardiac vagus in
humans. J Physiol 2005 Sep 1;567(Pt 2):713-21. | en |
dcterms.references | Benarroch EE. Central Autonomic Control. In: Robertson D, Biaggioni I, Burnstock
G, Low PA, Paton FR, editors. Primer on the Autonomic Nervous System. Tercera
ed. Academic Press; 2012. p. 9-12. | en |
dcterms.references | Critchley HD, Harrison NA. Visceral influences on brain and behavior. Neuron
2013 Feb 20;77(4):624-38. | en |
dcterms.references | Thayer JF, Hansen AL, Saus-Rose E, Johnsen BH. Heart rate variability, prefrontal
neural function, and cognitive performance: the neurovisceral integration
perspective on self-regulation, adaptation, and health. Ann Behav Med 2009
Apr;37(2):141-53 | en |
dcterms.references | Barbas H, Saha S, Rempel-Clower N, Ghashghaei T. Serial pathways from primate
prefrontal cortex to autonomic areas may influence emotional expression. BMC
Neurosci 2003 Oct 10;4:25. | en |
dcterms.references | Saha S. Role of the central nucleus of the amygdala in the control of blood
pressure: descending pathways to medullary cardiovascular nuclei. Clin Exp
Pharmacol Physiol 2005 May;32(5-6):450-6 | en |
dcterms.references | Hotamisligil GS. Inflammation and metabolic disorders. Nature 2006 Dec
14;444(7121):860-7. | en |
dcterms.references | de Rooij SR, Nijpels G, Nilsson PM, Nolan JJ, Gabriel R, Bobbioni-Harsch E, et al.
Low-grade chronic inflammation in the relationship between insulin sensitivity and cardiovascular disease (RISC) population: associations with insulin resistance
and cardiometabolic risk profile. Diabetes Care 2009 Jul;32(7):1295-301. | en |
dcterms.references | Popa C, Netea MG, van Riel PL, van der Meer JW, Stalenhoef AF. The role of TNFalpha in chronic inflammatory conditions, intermediary metabolism, and
cardiovascular risk. J Lipid Res 2007 Apr;48(4):751-62 | en |
dcterms.references | Tzanavari T, Giannogonas P, Karalis KP. TNF-alpha and obesity. Curr Dir
Autoimmun 2010;11:145-56. | en |
dcterms.references | Trzeciak-Ryczek A, Tokarz-Deptula B, Niedzwiedzka-Rystwej P, Deptula W.
Adipose tissue – component of the immune system. Centr Eur J Immunol
2011;36(2):95-9. | en |
dcterms.references | Wang M, Markel T, Crisostomo P, Herring C, Meldrum KK, Lillemoe KD, et al.
Deficiency of TNFR1 protects myocardium through SOCS3 and IL-6 but not p38
MAPK or IL-1beta. Am J Physiol Heart Circ Physiol 2007 Apr;292(4):H1694-H1699 | en |
dcterms.references | Kishore R, Tkebuchava T, Sasi SP, Silver M, Gilbert HY, Yoon YS, et al. Tumor
necrosis factor-alpha signaling via TNFR1/p55 is deleterious whereas TNFR2/p75
signaling is protective in adult infarct myocardium. Adv Exp Med Biol
2011;691:433-48. | en |
dcterms.references | Cortez-Cooper M, Meaders E, Stallings J, Haddow S, Kraj B, Sloan G, et al. Soluble
TNF and IL-6 receptors: indicators of vascular health in women without
cardiovascular disease. Vasc Med 2013 Oct;18(5):282-9. | en |
dcterms.references | Kleinbongard P, Heusch G, Schulz R. TNFalpha in atherosclerosis, myocardial
ischemia/reperfusion and heart failure. Pharmacol Ther 2010 Sep;127(3):295-
314 | en |
dcterms.references | Zhang H, Park Y, Wu J, Chen X, Lee S, Yang J, et al. Role of TNF-alpha in vascular
dysfunction. Clin Sci (Lond) 2009 Feb;116(3):219-30. | en |
dcterms.references | Glund S, Krook A. Role of interleukin-6 signalling in glucose and lipid metabolism.
Acta Physiol 2008;192:37-48. | en |
dcterms.references | Scheller J, Chalaris A, Schmidt-Arras D, Rose-John S. The pro- and antiinflammatory properties of the cytokine interleukin-6. Biochim Biophys Acta
2011 May;1813(5):878-88 | en |
dcterms.references | Demyanets S, Huber K, Wojta J. Vascular effects of glycoprotein130 ligands--part
I: pathophysiological role. Vascul Pharmacol 2012 Jan;56(1-2):34-46. | en |
dcterms.references | Pal M, Febbraio MA, Whitham M. From cytokine to myokine: the emerging role
of interleukin-6 in metabolic regulation. Immunol Cell Biol 2014 Apr;92(4):331-9. | en |
dcterms.references | Munoz-Canoves P, Scheele C, Pedersen BK, Serrano AL. Interleukin-6 myokine
signaling in skeletal muscle: a double-edged sword? FEBS J 2013
Sep;280(17):4131-48. | en |
dcterms.references | Fantuzzi G. Adiponectin in inflammatory and immune-mediated diseases.
Cytokine 2013 Oct;64(1):1-10. | en |
dcterms.references | Baldasseroni S, Antenore A, Di SC, Orso F, Lonetto G, Bartoli N, et al. Adiponectin,
diabetes and ischemic heart failure: a challenging relationship. Cardiovasc
Diabetol 2012;11:151. | en |
dcterms.references | Friedrichsen M, Mortensen B, Pehmoller C, Birk JB, Wojtaszewski JF. Exerciseinduced AMPK activity in skeletal muscle: role in glucose uptake and insulin
sensitivity. Mol Cell Endocrinol 2013 Feb 25;366(2):204-14. | en |
dcterms.references | Golbidi S, Badran M, Laher I. Antioxidant and anti-inflammatory effects of
exercise in diabetic patients. Exp Diabetes Res 2012;2012:941868. | en |
dcterms.references | Pepys MB, Hirschfield GM. C-reactive protein: a critical update. J Clin Invest 2003
Jun;111(12):1805-12. | en |
dcterms.references | Goldberg RB. Cytokine and cytokine-like inflammation markers, endothelial
dysfunction, and imbalanced coagulation in development of diabetes and its
complications. J Clin Endocrinol Metab 2009 Sep;94(9):3171-82. | en |
dcterms.references | Albert MA. Biomarkers and heart disease. J Clin Sleep Med 2011 Oct 15;7(5
Suppl):S9-11. | en |
dcterms.references | Hayashino Y, Jackson JL, Hirata T, Fukumori N, Nakamura F, Fukuhara S, et al.
Effects of exercise on C-reactive protein, inflammatory cytokine and adipokine in
patients with type 2 diabetes: a meta-analysis of randomized controlled trials.
Metabolism 2014 Mar;63(3):431-40. | en |
dcterms.references | Choi J, Joseph L, Pilote L. Obesity and C-reactive protein in various populations: a
systematic review and meta-analysis. Obes Rev 2013 Mar;14(3):232-44. | en |
dcterms.references | Finsterer J. Biomarkers of peripheral muscle fatigue during exercise. BMC
Musculoskeletal Disorders 2012;13(218):1-13. | en |
dcterms.references | Pierson RN. A brief history of body composition-from F. D. Moore to the new
Reference Man. Acta Diabetol 2003;40(Suppl 1):S114-S116. | en |
dcterms.references | Mattu HS, Randeva HS. Role of adipokines in cardiovascular disease. J Endocrinol
2013 Jan;216(1):T17-T36. | en |
dcterms.references | Korda M, Kubant R, Patton S, Malinski T. Leptin-induced endothelial dysfunction
in obesity. Am J Physiol Heart Circ Physiol 2008 Oct;295(4):H1514-H1521. | en |
dcterms.references | Swaroop JJ, Rajarajeswari D, Naidu JN. Association of TNF-alpha with insulin
resistance in type 2 diabetes mellitus. Indian J Med Res 2012;135:127-30. | en |
dcterms.references | Pedersen BK. Muscle as a secretory organ. Compr Physiol 2013 Jul;3(3):1337-62. | en |
dcterms.references | Leon-Ariza HH, Melo CA, Ramírez JF. Papel de la producción de miokinas a través
del ejercicio. J Sport Health Res 2012;4(2):157-66. | en |
dcterms.references | Catoire M, Mensink M, Kalkhoven E, Schrauwen P, Kersten S. Identification of
human exercise-induced myokines using secretome analysis. Physiol Genomics
2014 Apr 1;46(7):256-67. | en |
dcterms.references | Marosi K, Mattson MP. BDNF mediates adaptive brain and body responses to
energetic challenges. Trends Endocrinol Metab 2014 Feb;25(2):89-98. | en |
dcterms.references | Huh JY, Dincer F, Mesfum E, Mantzoros CS. Irisin stimulates muscle growthrelated genes and regulates adipocyte differentiation and metabolism in
humans. Int J Obes (Lond) 2014 Mar 11. | en |
dcterms.references | Nikolic VN, Jevtovic-Stoimenov T, Stokanovic D, Milovanovic M, VelickovicRadovanovic R, Pesic S, et al. An inverse correlation between TNF alpha serum
levels and heart rate variability in patients with heart failure. J Cardiol 2013
Jul;62(1):37-43. | en |
dcterms.references | Kang YM, He RL, Yang LM, Qin DN, Guggilam A, Elks C, et al. Brain tumour
necrosis factor-alpha modulates neurotransmitters in hypothalamic
paraventricular nucleus in heart failure. Cardiovasc Res 2009 Sep 1;83(4):737-46. | en |
dcterms.references | Wei SG, Zhang ZH, Beltz TG, Yu Y, Johnson AK, Felder RB. Subfornical organ
mediates sympathetic and hemodynamic responses to blood-borne
proinflammatory cytokines. Hypertension 2013 Jul;62(1):118-25. | en |
dcterms.references | Hoyda TD, Samson WK, Ferguson AV. Adiponectin depolarizes parvocellular
paraventricular nucleus neurons controlling neuroendocrine and autonomic
function. Endocrinology 2009 Feb;150(2):832-40. | en |
dcterms.references | Zapata P, Larrain C, Reyes P, Fernandez R. Immunosensory signalling by carotid
body chemoreceptors. Respir Physiol Neurobiol 2011 Sep 30;178(3):370-4. | en |
dcterms.references | Bellinger DL, Lorton D. Autonomic regulation of cellular immune function. Auton
Neurosci 2014 May;182:15-41. | en |
dcterms.references | Janig W. Sympathetic nervous system and inflammation: a conceptual view.
Auton Neurosci 2014 May;182:4-14. | en |
dcterms.references | Grisanti LA, Woster AP, Dahlman J, Sauter ER, Combs CK, Porter JE. alpha1-
adrenergic receptors positively regulate Toll-like receptor cytokine production
from human monocytes and macrophages. J Pharmacol Exp Ther 2011
Aug;338(2):648-57 | en |
dcterms.references | Martelli D, McKinley MJ, McAllen RM. The cholinergic anti-inflammatory
pathway: a critical review. Auton Neurosci 2014 May;182:65-9. | en |
dcterms.references | Downs AM, Bond CE, Hoover DB. Localization of alpha7 nicotinic acetylcholine
receptor mRNA and protein within the cholinergic anti-inflammatory pathway.
Neuroscience 2014 Apr 25;266:178-85. | en |
dcterms.references | Sun Y, Li Q, Gui H, Xu DP, Yang YL, Su DF, et al. MicroRNA-124 mediates the
cholinergic anti-inflammatory action through inhibiting the production of proinflammatory cytokines. Cell Res 2013 Nov;23(11):1270-83. | en |
dcterms.references | Cancello R, Zulian A, Maestrini S, Mencarelli M, Della BA, Invitti C, et al. The
nicotinic acetylcholine receptor alpha7 in subcutaneous mature adipocytes:
downregulation in human obesity and modulation by diet-induced weight loss.
Int J Obes (Lond) 2012 Dec;36(12):1552-7. | en |
dcterms.references | Dym CL. Principles of Mathematical Modeling. Segunda ed. San Diego (USA):
Elsevier; 2004. | en |
dcterms.references | Shiavi R. Introduction to Applied Statistical Signal Analysis. Tercera ed. California
USA: Elsevier; 2007. | en |
dcterms.references | Acharya UR, Suri JS, Spaan JAE, Krishnan SM. Advances in Cardiac Signal
Processing. Primera ed. Berlin (Alemania): Springer; 2007. | en |
dcterms.references | Migliaro ER, Canetti R, Contreras P, Hakas M, Eirea G, Machado A. Procesamiento
de señales para el estudio de la Variabilidad de la Frecuencia Cardiaca.
Procesamiento de señales e imágenes: Teoría y Aplicaciones.Buenos Aires
(Argentina): Facultad Regional de Buenos Aires, Universidad Tecnológica
Nacional; 2004. | en |
dcterms.references | Lessard CS. Signal Processing of Random Physiological Signals. Primera ed. Texas
(USA): Morgan & Claypool Publishers; 2006. | en |
dcterms.references | Cobelli C, Carson E. Introduction to Modeling in Physiology and Medicine.
Primera ed. Netherlands: Elsevier; 2008. | en |
dcterms.references | Smith S. The Scientist and Engineer's Guide to Digital Signal Processing. Segunda
ed. San Diego (USA): California Technical Publishing; 1999. | en |
dcterms.references | Khoo MCK. Physiological Control Systems, Analysis, Simulation, and Estimation.
Primera ed. New Jersey (USA): Wiley-Interscience; 2000. | en |
dcterms.references | Theis FJ, Meyer-Bäse A. Biomedical Signal Analysis: Contemporary Methods and
Applications. Primera ed. Massachusetts (USA): Massachusetts Institute of
Technology; 2010. | en |
dcterms.references | Tarvainen MP, Niskanen JP, Lipponen JA, Ranta-Aho PO, Karjalainen PA. Kubios
HRV--heart rate variability analysis software. Comput Methods Programs Biomed
2014;113(1):210-20. | en |
dcterms.references | Hernandez SR, Fernández CC. Metodología de la investigación. Primera ed.
México: McGraw-Hill Interamericana; 1991. | en |
dcterms.references | Rodriguez-Linares L, Lado MJ, Vila XA, Mendez AJ, Cuesta P. gHRV: Heart rate
variability analysis made easy. Comput Methods Programs Biomed 2014
Aug;116(1):26-38. | en |
dcterms.references | Chang CC, Hsu HY, Hsiao TC. The interpretation of very high frequency band of
instantaneous pulse rate variability during paced respiration. Biomed Eng Online
2014;13:46. | en |
dcterms.references | Vila XA, Lado MJ, Mendez AJ, Olivieri DN. An R package for Heart Rate Variability
analysis. IEEE International Symposium on Intelligent Signal Processing 2009;217-
22 | en |
dcterms.references | Kaufmann T, Sutterlin S, Schulz SM, Vogele C. ARTiiFACT: a tool for heart rate
artifact processing and heart rate variability analysis. Behav Res Methods 2011
Dec;43(4):1161-70. | en |
dcterms.references | Perakakis P, Joffily M, Taylor M, Guerra P, Vila J. KARDIA: a Matlab software for
the analysis of cardiac interbeat intervals. Comput Methods Programs Biomed
2010 Apr;98(1):83-9. | en |
dcterms.references | Vila BN, Rodriguez-Linares L, Cuesta P, Lado MJ, Mendez AJ, Vila XA. gVARVI: A
graphical software tool for the acquisition of the heart rate in response to
external stimuli. Comput Methods Programs Biomed 2016 Aug;132:197-205 | en |
dcterms.references | Klemenc M, Strumbelj E. Predicting the outcome of head-up tilt test using heart
rate variability and baroreflex sensitivity parameters in patients with vasovagal
syncope. Clin Auton Res 2015 Dec;25(6):391-8. | en |
dcterms.references | Maestri R, Pinna GD. POLYAN: a computer program for polyparametric analysis
of cardio-respiratory variability signals. Comput Methods Programs Biomed 1998
Apr;56(1):37-48 | en |
dcterms.references | Shafiq H, McGregor C, Murphy B. The impact of cervical manipulation on heart
rate variability. Conf Proc IEEE Eng Med Biol Soc 2014;2014:3406-9. | en |
dcterms.references | Evans S, Seidman LC, Tsao JC, Lung KC, Zeltzer LK, Naliboff BD. Heart rate
variability as a biomarker for autonomic nervous system response differences
between children with chronic pain and healthy control children. J Pain Res
2013;6:449-57 | en |
dcterms.references | Polar. RS800CX Manual del Usuario. http://support polar
com/e_manuals/RS800CX/Polar_RS800CX_user_manual_Espanol/manual pdf
2013 | en |
dcterms.references | Hynynen E, Konttinen N, Kinnunen U, Kyrolainen H, Rusko H. The incidence of
stress symptoms and heart rate variability during sleep and orthostatic test. Eur J
Appl Physiol 2011 May;111(5):733-41. | en |
dcterms.references | Malik M. Heart rate variability: standards of measurement, physiological
interpretation and clinical use. Task Force of the European Society of Cardiology
and the North American Society of Pacing and Electrophysiology. Circulation
1996 Mar 1;93(5):1043-65. | en |
dcterms.references | Peltola MA. Role of editing of R-R intervals in the analysis of heart rate variability.
Front Physiol 2012;3:148. | en |
dcterms.references | Boor C. A Practical Guide to Splines. Primera ed. New-York: Springer; 1978. | en |
dcterms.references | Boardman A, Schlindwein FS, Rocha AP, Leite A. A study on the optimum order of
autoregressive models for heart rate variability. Physiol Meas 2002
May;23(2):325-36. | en |
dcterms.references | Kim KK, Baek HJ, Lim YG, Park KS. Effect of missing RR-interval data on nonlinear
heart rate variability analysis. Comput Methods Programs Biomed 2012
Jun;106(3):210-8 | en |
dcterms.references | Tarvainen MP, Ranta-Aho PO, Karjalainen PA. An advanced detrending method
with application to HRV analysis. IEEE Trans Biomed Eng 2002 Feb;49(2):172-5 | en |
dcterms.references | Heart rate variability: standards of measurement, physiological interpretation
and clinical use. Task Force of the European Society of Cardiology and the North
American Society of Pacing and Electrophysiology. Circulation 1996 Mar
1;93(5):1043-65. | en |
dcterms.references | Sinnreich R, Kark JD, Friedlander Y, Sapoznikov D, Luria MH. Five minute
recordings of heart rate variability for population studies: repeatability and agesex characteristics. Heart 1998 Aug;80(2):156-62. | en |
dcterms.references | Akselrod S, Gordon D, Ubel FA, Shannon DC, Berger AC, Cohen RJ. Power
spectrum analysis of heart rate fluctuation: a quantitative probe of beat-to-beat
cardiovascular control. Science 1981 Jul 10;213(4504):220-2. | en |
dcterms.references | Montano N, Ruscone TG, Porta A, Lombardi F, Pagani M, Malliani A. Power
spectrum analysis of heart rate variability to assess the changes in
sympathovagal balance during graded orthostatic tilt. Circulation 1994
Oct;90(4):1826-31. | en |
dcterms.references | Moody GB. Spectral analysis of heart rate without resampling. London UK. 1993. | en |
dcterms.references | Perini R, Orizio C, Baselli G, Cerutti S, Veicsteinas A. The influence of exercise
intensity on the power spectrum of heart rate variability. Eur J Appl Physiol
Occup Physiol 1990;61(1-2):143-8. | en |
dcterms.references | Burr RL. Interpretation of normalized spectral heart rate variability indices in
sleep research: a critical review. Sleep 2007 Jul;30(7):913-9. | en |
dcterms.references | Lombardi F. Chaos theory, heart rate variability, and arrhythmic mortality.
Circulation 2000 Jan 4;101(1):8-10. | en |
dcterms.references | Carrasco S, Gaitan MJ, Gonzalez R, Yanez O. Correlation among Poincare plot
indexes and time and frequency domain measures of heart rate variability. J Med
Eng Technol 2001 Nov;25(6):240-8 | en |
dcterms.references | Brennan M, Palaniswami M, Kamen P. Do existing measures of Poincare plot
geometry reflect nonlinear features of heart rate variability? IEEE Trans Biomed
Eng 2001 Nov;48(11):1342-7. | en |
dcterms.references | Toichi M, Sugiura T, Murai T, Sengoku A. A new method of assessing cardiac
autonomic function and its comparison with spectral analysis and coefficient of
variation of R-R interval. J Auton Nerv Syst 1997 Jan 12;62(1-2):79-84. | en |
dcterms.references | Fusheng Y, Bo H, Qingyu T. Approximate Entropy and Its Application to Biosignal
Analysis. In: Akay M, editor. Nonlinear Biomedical Signal Processing: Dynamic
Analysis and Modeling volume II.New York: IEEE Press; 2012. | en |
dcterms.references | Richman JS, Moorman JR. Physiological time-series analysis using approximate
entropy and sample entropy. Am J Physiol Heart Circ Physiol 2000
Jun;278(6):H2039-H2049. | en |
dcterms.references | Peng CK, Havlin S, Stanley HE, Goldberger AL. Quantification of scaling exponents
and crossover phenomena in nonstationary heartbeat time series. Chaos
1995;5(1):82-7. | en |
dcterms.references | Penzel T, Kantelhardt JW, Grote L, Peter JH, Bunde A. Comparison of detrended
fluctuation analysis and spectral analysis for heart rate variability in sleep and
sleep apnea. IEEE Trans Biomed Eng 2003 Oct;50(10):1143-51. | en |
dcterms.references | Heymsfield SB, Wang Z, Baumgartner RN, Ross R. Human body composition:
advances in models and methods. Annu Rev Nutr 1997;17:527-58. | en |
dcterms.references | Amato MC, Guarnotta V, Giordano C. Body composition assessment for the
definition of cardiometabolic risk. J Endocrinol Invest 2013 Jul;36(7):537-43. | en |
dcterms.references | Gierach M, Gierach J, Ewertowska M, Arndt A, Junik R. Correlation between Body
Mass Index and Waist Circumference in Patients with Metabolic Syndrome. ISRN
Endocrinol 2014;2014:514589. | en |
dcterms.references | Ellis KJ. Selected body composition methods can be used in field studies. J Nutr
2001;131(5):1589S-95S. | en |
dcterms.references | Pedersen BK. Muscle as a secretory organ. Compr Physiol 2013 Jul;3(3):1337-62. | en |
dcterms.references | Brandt C, Pedersen BK. The role of exercise-induced myokines in muscle
homeostasis and the defense against chronic diseases. J Biomed Biotechnol
2010;2010:520258. | en |
dcterms.references | Fasshauer M, Bluher M. Adipokines in health and disease. Trends Pharmacol Sci
2015 Jul;36(7):461-70. | en |
dcterms.references | Carter JL. Somatotipo. In: Norton K, Olds T, editors. Antropométrica. Primera ed.
Rosario (Argentina): Biosystem; 1996. p. 99-115. | en |
dcterms.references | Leon-Ariza HH, Torres AM, Arias I, Zea-Robles AC. Análisis del índice de masa
corporal, porcentaje de grasa y somatotipo en estudiantes universitarios de
primer semestre. Revista de Investigación: Cuerpo, Cultura y Movimiento
2013;2(3 - 4):37-49 | en |
dcterms.references | Peterson HR, Rothschild M, Weinberg CR, Fell RD, McLeish KR, Pfeifer MA. Body
fat and the activity of the autonomic nervous system. N Engl J Med 1988 Apr
28;318(17):1077-83. | en |
dcterms.references | Poehlman ET, Gardner AW, Goran MI, Arciero PJ, Toth MJ, Ades PA, et al.
Sympathetic nervous system activity, body fatness, and body fat distribution in
younger and older males. J Appl Physiol (1985 ) 1995 Mar;78(3):802-6. | en |
dcterms.references | Virtanen R, Jula A, Kuusela T, Helenius H, Voipio-Pulkki LM. Reduced heart rate
variability in hypertension: associations with lifestyle factors and plasma renin
activity. J Hum Hypertens 2003 Mar;17(3):171-9. | en |
dcterms.references | Kudat H, Akkaya V, Sozen AB, Salman S, Demirel S, Ozcan M, et al. Heart rate
variability in diabetes patients. J Int Med Res 2006 May;34(3):291-6. | en |
dcterms.references | Kim JA, Park YG, Cho KH, Hong MH, Han HC, Choi YS, et al. Heart rate variability
and obesity indices: emphasis on the response to noise and standing. J Am Board
Fam Pract 2005 Mar;18(2):97-103. | en |
dcterms.references | Molfino A, Fiorentini A, Tubani L, Martuscelli M, Rossi FF, Laviano A. Body mass
index is related to autonomic nervous system activity as measured by heart rate
variability. Eur J Clin Nutr 2009 Oct;63(10):1263-5. | en |
dcterms.references | Rutherford WJ, Diemer GA, Scott ED. Comparison of Bioelectrical Impedance and
Skinfolds with Hydrodensitometry in the Assessment of Body Composition in
Healthy Young Adults. ICHPER-SD Journal of Research 2011;6(2):56-60. | en |
dcterms.references | International Society for the Advancement of Kinanthropometry. International
Standards for Anthropometric Assessment. Primera ed. Underdale (Australia):
ISAK; 2001. | en |
dcterms.references | Ivorra A. Bioimpedance Monitoring for physicians: an overview. Centre Nacional
de Microelectrònica Biomedical Applications Group 2003;1-35. | en |
dcterms.references | Kyle UG, Bosaeus I, De Lorenzo AD, Deurenberg P, Elia M, Gomez JM, et al.
Bioelectrical impedance analysis--part I: review of principles and methods. Clin
Nutr 2004 Oct;23(5):1226-43 | en |
dcterms.references | Khalil SF, Mohktar MS, Ibrahim F. The theory and fundamentals of bioimpedance
analysis in clinical status monitoring and diagnosis of diseases. Sensors (Basel)
2014;14(6):10895-928. | en |
dcterms.references | Bolfe VJ, Ribas S, I, Montebelo MIL, Guirro RRJ. Electrical impedance behavior of
biological tissues during trascutaneus electrical stimulation. Rev Bras fisioter
2007;11(2):135-45. | en |
dcterms.references | Yuhasz MS. Physiscal Fitness Manual. London Ontario: Universidad de Western
Ontario; 1974. | en |
dcterms.references | Doupe MB, Martin AD, Searle MS, Kriellaars DJ, Giesbrecht GG. A new Formula
for Population-Based Estimation of Whole Body Muscle Mass in Males. Can J
Appl Physiol 2010;22(6):598-608. | en |
dcterms.references | Rocha MSL. Peso ósseo do brasileiro de ambos os sexos de 17 a 25 años. Arq
Anat Antrop 1975;1:445-51. | en |
dcterms.references | Carter JL. The Heath-Carter Anthropometric somatotype -Instruction manual-.
San Diego: Department of Exercise and Nutritional Sciences; 2002. | en |
dcterms.references | Ross WD, Marfell-Jones M. Kineanthropometry. In: MacDougal J, Wenger H,
Green H, editors. Physiological Tests for Elite Athletes. Segunda ed. Champaign
(IL): Human Kinetics; 1991. p. 223-308. | en |
dcterms.references | Tarvainen MP, Ranta-Aho PO, Karjalainen PA. An advanced detrending method
with application to HRV analysis. IEEE Trans Biomed Eng 2002 Feb;49(2):172-5. | en |
dcterms.references | Carter JL. The Heath-Carter somatotype method. San Diego State University
1975. | en |
dcterms.references | Pescatello LS. Health-Related Physical Fitness Testing and Interpretation. In:
Thompson PD, editor. Guidelines for Exercise Testing and Prescription. Novena
ed. Filadelfia (USA): ACSM; 2014. p. 72-107. | en |
dcterms.references | Khalil SF, Mohktar MS, Ibrahim F. The theory and fundamentals of bioimpedance
analysis in clinical status monitoring and diagnosis of diseases. Sensors (Basel)
2014;14(6):10895-928. | en |
dcterms.references | Bland JM, Altman DG. Statistical methods for assessing agreement between two
methods of clinical measurement. Lancet 1986 Feb 8;1(8476):307-10 | en |
dcterms.references | Koenig J, Jarczok MN, Warth M, Ellis RJ, Bach C, Hillecke TK, et al. Body mass
index is related to autonomic nervous system activity as measured by heart rate
variability--a replication using short term measurements. J Nutr Health Aging
2014 Mar;18(3):300-2. | en |
dcterms.references | Koenig J, Windham BG, Ferrucci L, Sonntag D, Fischer JE, Thayer JF, et al.
Association Strength of Three Adiposity Measures with Autonomic Nervous
System Function in Apparently Healthy Employees. J Nutr Health Aging 2015
Nov;19(9):879-82. | en |
dcterms.references | Esco MR, Williford HN. Race influences the relationship between aerobic power
and heart rate recovery. J Sports Med Phys Fitness 2013 Dec;53(6):583-7. | en |
dcterms.references | Baek J, Park D, Kim I, Won JU, Hwang J, Roh J. Autonomic dysfunction of
overweight combined with low muscle mass. Clin Auton Res 2013 Dec;23(6):325-
31. | en |
dcterms.references | Koenig J, Thayer JF. Sex differences in healthy human heart rate variability: A
meta-analysis. Neurosci Biobehav Rev 2016 May;64:288-310. | en |
dcterms.references | Tanu A, Jyotsna S. A Comparative Study Of Heart Rate Variability Between Pre
And Post Menopausal Women From Health Care Profession. IJBAP 2012;1(1):49-
52 | en |
dcterms.references | Yildirir A, Kabakci G, Akgul E, Tokgozoglu L, Oto A. Effects of menstrual cycle on
cardiac autonomic innervation as assessed by heart rate variability. Ann
Noninvasive Electrocardiol 2002 Jan;7(1):60-3. | en |
dcterms.references | Du XJ, Fang L, Kiriazis H. Sex dimorphism in cardiac pathophysiology:
experimental findings, hormonal mechanisms, and molecular mechanisms.
Pharmacol Ther 2006 Aug;111(2):434-75 | en |
dcterms.references | Wranicz JK, Rosiak M, Cygankiewicz I, Kula P, Kula K, Zareba W. Sex steroids and
heart rate variability in patients after myocardial infarction. Ann Noninvasive
Electrocardiol 2004 Apr;9(2):156-61. | en |
dcterms.references | Montano N, Porta A, Cogliati C, Costantino G, Tobaldini E, Casali KR, et al. Heart
rate variability explored in the frequency domain: a tool to investigate the link
between heart and behavior. Neurosci Biobehav Rev 2009 Feb;33(2):71-80. | en |
dcterms.references | Somlev P. The Effects of Orthostatic Test on Poincaré Plot Indexes of Heart Rate
Variability in Trained and Untrained Subjects. Research in Kinesiology
2015;43(1):71-6 | en |
dcterms.references | da Silva VP, de Oliveira NA, Silveira H, Mello RG, Deslandes AC. Heart rate
variability indexes as a marker of chronic adaptation in athletes: a systematic
review. Ann Noninvasive Electrocardiol 2015 Mar;20(2):108-18. | en |
dcterms.references | Townend JN, al-Ani M, West JN, Littler WA, Coote JH. Modulation of cardiac
autonomic control in humans by angiotensin II. Hypertension 1995
Jun;25(6):1270-5 | en |
dcterms.references | Kraemer WJ, Ratamess NA. Hormonal responses and adaptations to resistance
exercise and training. Sports Med 2005;35(4):339-61. | en |
dcterms.references | Kishi T. Regulation of the sympathetic nervous system by nitric oxide and
oxidative stress in the rostral ventrolateral medulla: 2012 Academic Conference
Award from the Japanese Society of Hypertension. Hypertens Res 2013
Oct;36(10):845-51. | en |
dcterms.references | Oliveira NL, Ribeiro F, Alves AJ, Teixeira M, Miranda F, Oliveira J. Heart rate
variability in myocardial infarction patients: effects of exercise training. Rev Port
Cardiol 2013 Sep;32(9):687-700. | en |
dcterms.references | Eikelis N, Schlaich M, Aggarwal A, Kaye D, Esler M. Interactions between leptin
and the human sympathetic nervous system. Hypertension 2003
May;41(5):1072-9. | en |
dcterms.references | Grill HJ. Distributed neural control of energy balance: contributions from
hindbrain and hypothalamus. Obesity (Silver Spring) 2006 Aug;14 Suppl 5:216S21S. | en |
dcterms.references | Mark AL, Agassandian K, Morgan DA, Liu X, Cassell MD, Rahmouni K. Leptin
signaling in the nucleus tractus solitarii increases sympathetic nerve activity to
the kidney. Hypertension 2009 Feb;53(2):375-80. | en |
dcterms.references | Zapata P, Larrain C, Reyes P, Fernandez R. Immunosensory signalling by carotid
body chemoreceptors. Respir Physiol Neurobiol 2011 Sep 30;178(3):370-4. | en |
dcterms.references | Florian JP, Pawelczyk JA. Non-esterified fatty acids increase arterial pressure via
central sympathetic activation in humans. Clin Sci (Lond) 2010 Jan;118(1):61-9. | en |
dcterms.references | Gadegbeku CA, Dhandayuthapani A, Sadler ZE, Egan BM. Raising lipids acutely
reduces baroreflex sensitivity. Am J Hypertens 2002 Jun;15(6):479-85. | en |
dcterms.references | Smith MM, Minson CT. Obesity and adipokines: effects on sympathetic
overactivity. J Physiol 2012 Apr 15;590(8):1787-801. | en |
dcterms.references | Benatti FB, Pedersen BK. Exercise as an anti-inflammatory therapy for rheumatic
diseases-myokine regulation. Nat Rev Rheumatol 2015 Feb;11(2):86-97. | en |
dcterms.references | Sanchez-Jimenez R, Alvarado-Vasquez N. IL-15 that a regulator of TNF-alpha in
patients with diabetes mellitus type 2. Med Hypotheses 2013 Jun;80(6):776-7. | en |
dcterms.references | Sa-Nguanmoo P, Chattipakorn N, Chattipakorn SC. Potential roles of fibroblast
growth factor 21 in the brain. Metab Brain Dis 2016 Apr;31(2):239-48. | en |
dcterms.references | Marosi K, Mattson MP. BDNF mediates adaptive brain and body responses to
energetic challenges. Trends Endocrinol Metab 2014 Feb;25(2):89-98. | en |
dcterms.references | Hummasti S, Hotamisligil GS. Endoplasmic reticulum stress and inflammation in
obesity and diabetes. Circ Res 2010 Sep 3;107(5):579-91. | en |
dcterms.references | Pedersen BK, Fischer CP. Beneficial health effects of exercise – the role of IL-6 as
a myokine. Trends Pharmacol Sci 2007;28(4):152-6. | en |
dcterms.references | Moreno V, I, Golabkesh Z, Kallberg H, Leander K, de FU, Gigante B. Circulating
levels of interleukin 6 soluble receptor and its natural antagonist, sgp130, and
the risk of myocardial infarction. Atherosclerosis 2015 Jun;240(2):477-81. | en |
dcterms.references | Groot HE, Hartman MH, Gu YL, de Smet BJ, van den Heuvel AF, Lipsic E, et al.
Soluble interleukin 6 receptor levels are associated with reduced myocardial
reperfusion after percutaneous coronary intervention for acute myocardial
infarction. Cytokine 2015 Jun;73(2):207-12 | en |
dcterms.references | Weiss TW, Arnesen H, Seljeflot I. Components of the interleukin-6 transsignalling
system are associated with the metabolic syndrome, endothelial dysfunction and
arterial stiffness. Metabolism 2013 Jul;62(7):1008-13. | en |
dcterms.references | Ravi AK, Khurana S, Lemon J, Plumb J, Booth G, Healy L, et al. Increased levels of
soluble interleukin-6 receptor and CCL3 in COPD sputum. Respir Res
2014;15:103. | en |
dcterms.references | Cortez-Cooper M, Meaders E, Stallings J, Haddow S, Kraj B, Sloan G, et al. Soluble
TNF and IL-6 receptors: indicators of vascular health in women without
cardiovascular disease. Vasc Med 2013 Oct;18(5):282-9. | en |
dcterms.references | Wang J, Wang Q, Han T, Li YK, Zhu SL, Ao F, et al. Soluble interleukin-6 receptor | en |
thesis.degree.discipline | Facultad de Ingeniería | es_CO |
thesis.degree.level | Doctorado en Biociencias | es_CO |
thesis.degree.name | Doctor en Biociencias | es_CO |