@misc{10818/51899, year = {2022}, month = {8}, url = {http://hdl.handle.net/10818/51899}, abstract = {Critically ill patients with COVID-19 have important risk factors for the occurrence of 21 drug-drug interactions. The aim of this study was to characterize and describe the profile and 22 management of drug-drug interactions in critically ill patients affected by COVID-19 in a tertiary 23 care hospital in Colombia. A descriptive retrospective cohort with an exploratory analytical com- 24 ponent was performed. The medical records of 191 patients were reviewed from August 2020 to 25 February 2021. An initial descriptive analysis was performed, and a bivariate approach was de- 26 veloped to include variables of significance in a multivariate analysis. In our cohort of critically ill 27 patients the following factors were associated with a higher risk of major outcome development: a 28 higher age, Charlson comorbidity index (CCI), Sequential Organ Failure Assessment (SOFA) 29 score, a greater number of prescribed drugs, number of interactions, and the presence of type D 30 interactions.}, publisher = {Universidad de La Sabana}, title = {FARMACOVID : Retrospective cohort study of the profile and 2 management of drug interactions in critically ill patients with 3 COVID-19 in a tertiary care hospital in Colombia}, doi = {10.3390/xxxxx}, author = {López Cárdenas, Rigoberto Junior and Blanco Mejía, Jhosep Andrés and Lechtig, Sharon and Cruz González, Andrés Felipe and Fuentes Barreiro, Yuli Viviana and Diaz Pinilla, Nicolas and Liebisch Rey, Hans Nicolas and Pinedo Agudelo, Jennifer Andrea and Bastidas Gutiérrez, Nicolas David and Ortega Gómez, María Jose}, }