@article{10818/47479, year = {2001}, month = {8}, url = {http://hdl.handle.net/10818/47479}, abstract = {A total of 1073 infectious episodes (IEs) that occurred in 620 consecutive heart transplantation patients at Stanford Medical Center between 16 December 1980 and 30 June 1996 were reviewed. Infectious complications were a major cause of morbidity and mortality, second only to rejection as the cause of early deaths and the most common cause of late deaths. Of the IEs, 468 (43.6%) were caused by bacteria, 447 (41.7%) by viruses, 109 (10.2%) by fungi, 43 (4.0%) by Pneumocystis carinii, and 6 (0.6%) by protozoa. The largest number of IEs occurred in the lungs (301 [28.1%]). A significant reduction in the incidence of IEs and a delay in presentation after transplantation were observed; these were most likely related to the introduction of new chemoprophylactic regimens during the study period and prevention of significant disease caused by cytomegalovirus.}, abstract = {Se revisaron un total de 1073 episodios infecciosos (IE) que ocurrieron en 620 pacientes consecutivos con trasplantes de corazón en el Stanford Medical Center entre el 16 de diciembre de 1980 y el 30 de junio de 1996. Las complicaciones infecciosas fueron una de las principales causas de morbilidad y mortalidad, superadas solo por el rechazo como causa de muertes tempranas y la causa más común de muertes tardías. De las EI, 468 (43,6%) fueron causadas por bacterias, 447 (41,7%) por virus, 109 (10,2%) por hongos, 43 (4,0%) por Pneumocystis carinii y 6 (0,6%) por protozoos. El mayor número de EA se produjo en los pulmones (301 [28,1%]). Se observó una reducción significativa en la incidencia de EI y un retraso en la presentación después del trasplante.}, publisher = {Enfermedades Infecciosas Clínicas}, title = {Complicaciones infecciosas entre 620 pacientes consecutivos con trasplante de corazón en el Centro Médico de la Universidad de Stanford}, title = {Infectious Complications among 620 Consecutive Heart Transplant Patients at Stanford University Medical Center}, doi = {10.1086/322733}, author = {Montoya, J.G. and Giraldo, L.F. and Efron, B. and Stinson, E.B . and Gamberg, P. and Hunt, S. and Giannetti, N. and Miller, J. and Remington, J.S.}, }