TY - GEN AU - Londono, John AU - Santos, Ana Maria AU - Santos, Pedro Ivan AU - Cubidez, Maria Fernanda AU - Guzman, Claudia AU - Valle OƱate, Rafael PY - 2012 UR - http://hdl.handle.net/10818/57842 AB - Introduction: The combination of methotrexate (MTX) + leflunomide (LFN) has been shown to be effective in the treatment of RA. Its safety has been questioned. Objective: To evaluate the effectiveness and safety of the combination of MTX + LFN in... AB - Introduccion: La combinacion de metotrexato (MTX) + leflunomida (LFN) ha demostrado ser eficaz en el tratamiento de la AR. Su seguridad ha sido cuestionada. Objetivo: Evaluar la efectividad y seguridad de la combinacion de MTX + LFN en pacientes... LA - eng PB - Revista Brasileira de Reumatologia KW - Eficacia terapeutica KW - Seguridad del metotrexato KW - Leflunomida KW - Artritis reumatoide KW - Therapeutic efficacy KW - Safety of methotrexate KW - Leflunomide KW - Rheumatoid arthritis TI - Therapeutic efficacy and safety of methotrexate + leflunomide in Colombian patients with active rheumatoid arthritis refractory to conventional treatment ER -