TY - GEN 
AU - Hernan Yupanqui-Lozno
AU - Raul A. Bastarrachea
AU - Maria E. Yupanqui-Velazco
AU - Monica Alvarez-Jaramillo
AU - Esteban Medina-Méndez
AU - Aida P. Giraldo-Peña
PY - 2019
SN - 20734425
UR - http://hdl.handle.net/10818/62290
AB - Background: Congenital leptin deficiency is a recessive genetic disorder associated with severe early-onset obesity. It is caused by mutations in the leptin (LEP) gene, which encodes the protein product leptin. These mutations may cause...
AB - Antecedentes: la deficiencia congenita de leptina es un trastorno genetico recesivo asociado con obesidad grave de aparicion temprana. Es causada por mutaciones en el gen de la leptina (LEP), que codifica el producto proteico leptina. Estas mutaciones...
LA - spa
PB - Genes
KW - Colombian sisters
KW - LEP gene
KW - Congenital leptin deficiency
KW - Consanguinity
KW - Extreme obesity
KW - Novel mutation
TI - Congenital leptin deficiency and leptin gene missense mutation found in two colombian sisters with severe obesity
DO - 10.3390/genes10050342.
ER -