TY - GEN AU - Manry, Jérémy AU - Bastard, Paul AU - Gervais, Adrian AU - Le Voyer, Tom AU - Rosain, Jérémie PY - 2022 SN - 0027-8424 UR - http://hdl.handle.net/10818/54597 AB - Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection fatality rate (IFR) doubles with every 5 y of age from childhood onward. Circulating autoantibodies neutralizing IFN-α, IFN-ω, and/or IFN-β are found in ∼20% of deceased patients... LA - eng PB - Proceedings of the National Academy of Sciences of the United States of America KW - COVID-19 KW - Autoantibodies KW - Infection fatality rate KW - Relative risk KW - Type I KW - IFNs TI - The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies DO - 10.1073/pnas.2200413119 ER -