%0 Generic
%A Tuta-Quintero E.
%A Bastidas A.R.
%A Faizal-Gómez K.
%A Torres-Riveros S.G.
%A Rodríguez-Barajas D.A.
%A Guezguan J.A.
%A Muñoz L.D.
%A Rojas A.C.
%A Calderón K.H.
%A Velasco N.V.A.
%A Prieto P.
%A Cuestas J.
%A Camacho-Osorio J.
%A Bonilla G.
%A Bahamon E.C.
%A Guardiola M.A.
%A Salazar D.L.
%A Fajardo L.P.
%A Rincón-Hernández J.
%8 2024
%U http://hdl.handle.net/10818/63317
%X Background: Survival in patients with sleep apnoea (SA) can be reduced by variables such as age, sex, and comorbidities. However, survival data in patients with SA in Colombia remains scarce. Methods: This is a retrospective cohort study of patients diagnosed with SA between 2005 and 2022. Five-year survival was assessed using the Kaplan-Meier method, and survival curves were stratified by age, sex, and cardiovascular disease. Risk factors associated with survival were evaluated using Hazard Ratio (HR) by adjusting for confounding variables with a Cox regression model. A minimum sample size of 1537 patients were estimated to be necessary to estimate a survival incidence rate with a 5% precision. Results: The five-year survival rate in the general population was 94.6%, with lower survival in patients over 65 years (88.5% vs 97.9%; p < 0.001) and in patients with cardiovascular disease (89% vs 95.2%; p < 0.001) compared to the control group. In the Cox regression, age showed an HR of 1.05 (95% CI: 1.02–1.07; p < 0.001). Male sex had an HR of 2.31 (95% CI: 1.25–4.25; p = 0.007), congestive heart failure an HR of 4.00 (95% CI: 2.31–6.94; p < 0.001), chronic obstructive pulmonary disease (COPD) an HR of 1.75 (95% CI: 1.04–2.96; p = 0.035), chronic kidney disease (CKD) an HR of 2.23 (95% CI: 1.31–3.78; p = 0.003), and metastatic cancer an HR of 4.96 (95% CI: 1.95–12.60; p = 0.001). Conclusion: The study showed a high five-year survival rate in patients with SA. The risk factors associated with decreased overall five-year survival were age, male sex, cardiovascular disease, COPD, CKD, and metastatic cancer. © 2024 Tuta-Quintero et al.
%I Nature and Science of Sleep
%T Survival and Risk Factors Associated with Mortality in Patients with Sleep Apnoea in Colombia: A Retrospective Cohort Study
%R 10.2147/NSS.S481010
%~ Intellectum