%0 Generic
%A Pazukhina E.
%A Garcia-Gallo E.
%A Reyes L.F.
%A Kildal A.B.
%A Jassat W.
%A Dryden M.
%A Holter J.C.
%A Chatterjee A.
%A Gomez K.
%A Søraas A.
%A Puntoni M.
%A Latronico N.
%A Bozza F.A.
%A Edelstein M.
%A Gonçalves B.P.
%A Kartsonaki C.
%A Kruglova O.
%A Gaião S.
%A Chow Y.P.
%A Doshi Y.
%A Duque Vallejo S.I.
%A Ibáñez-Prada E.D.
%A Fuentes Y.V.
%A Hastie C.
%A O'Hara M.E.
%A Balan V.
%A Menkir T.
%A Merson L.
%A Kelly S.
%A Citarella B.W.
%A Semple M.G.
%A Scott J.T.
%A Munblit D.
%A Sigfrid L.
%8 2024
%U http://hdl.handle.net/10818/63283
%X Introduction A proportion of people develop Long Covid after acute COVID-19, but with most studies concentrated in high-income countries (HICs), the global burden is largely unknown. Our study aims to characterise long-term COVID-19 sequelae in populations globally and compare the prevalence of reported symptoms in HICs and low-income and middle-income countries (LMICs). Methods A prospective, observational study in 17 countries in Africa, Asia, Europe and South America, including adults with confirmed COVID-19 assessed at 2 to <6 and 6 to <12 months post-hospital discharge. A standardised case report form developed by International Severe Acute Respiratory and emerging Infection Consortium's Global COVID-19 Follow-up working group evaluated the frequency of fever, persistent symptoms, breathlessness (MRC dyspnoea scale), fatigue and impact on daily activities. Results Of 11 860 participants (median age: 52 (IQR: 41-62) years; 52.1% females), 56.5% were from HICs and 43.5% were from LMICs. The proportion identified with Long Covid was significantly higher in HICs vs LMICs at both assessment time points (69.0% vs 45.3%, p<0.001; 69.7% vs 42.4%, p<0.001). Participants in HICs were more likely to report not feeling fully recovered (54.3% vs 18.0%, p<0.001; 56.8% vs 40.1%, p<0.001), fatigue (42.9% vs 27.9%, p<0.001; 41.6% vs 27.9%, p<0.001), new/persistent fever (19.6% vs 2.1%, p<0.001; 20.3% vs 2.0%, p<0.001) and have a higher prevalence of anxiety/depression and impact on usual activities compared with participants in LMICs at 2 to <6 and 6 to <12 months post-COVID-19 hospital discharge, respectively.
%I BMJ Global Health
%T Long Covid: a global health issue - a prospective, cohort study set in four continents
%R 10.1136/bmjgh-2024-015245
%~ Intellectum