%0 Generic
%A Agudelo-Pérez S
%A Troncoso G
%A Roa A
%A Ariza A.G
%A Doumat G
%A Reinoso N.M
%A Botero-Rosas D.
%8 2024
%@ 2719535X
%U http://hdl.handle.net/10818/62236
%X Introduction: Perinatal asphyxia, a leading cause of neonatal mortality and neurological sequelae, necessitates early detection of pathophysiological neurologic changes during hypoxic-ischaemic encephalopathy (HIE). This study aimed to review published data on rScO2 monitoring during hypothermia treatment in neonates with perinatal asphyxia to predict short- and long-term neurological injury. Methods: A systematic review was performed using the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. Study identification was performed through a search between November and December 2021 in the electronic databases PubMed, Embase, Lilacs, Scopus, Web of Science, and Cochrane Central Register of Controlled Trials (CENTRAL). The main outcome was short-term (Changes in brain magnetic resonating imaging) and long-term (In neurodevelopment) neurological injury. The study protocol was registered in PROSPERO (International Prospective Register of Systematic Reviews) with CRD42023395438. Results: 380 articles were collected from databases in the initial search. Finally, 15 articles were selected for extraction and analysis of the information. An increase in rScO2 measured by NIRS (Near-infrared spectroscopy) at different moments of treatment predicts neurological injury. However, there exists a wide variability in the methods and outcomes of the studies. Conclusion: High rScO2 values were found to predict negative outcomes, with substantial discord among studies. NIRS is proposed as a real-time bedside tool for predicting brain injury in neonates with moderate to severe HIE. © 2024 Sergio Agudelo-Pérez et al., published by Sciendo.
%I Journal of Mother and Child
%T Cerebral rsco2 measured by near-infrared spectroscopy (nirs) during therapeutic hypothermia in neonates with hypoxic-ischemic encephalopathy: a systematic review
%R 10.34763/jmotherandchild.20242801.d-24-00010
%~ Intellectum