%0 Thesis
%A Ávila Celis, Paula Andrea
%A Oliveros Rodríguez, Henry
%A Agudelo Pérez, Sergio Iván
%A Cifuentes Serrano, Annie Alexandra
%8 2022-02-02
%U http://hdl.handle.net/10818/50995
%X Introduction: In low and middle-income countries the leading cause of neonatal 
mortality are acute birth events and perinatal asphyxia, training in neonatal 
resuscitation has been shown to decrease these causes of mortality. The program 
"Helping Babies Breathe" is a basic neonatal resuscitation program, which aims to 
strengthening neonatal resuscitation with five simple steps to follow that effectively 
resuscitate infants: adequate respiratory support with a mask bag, thermoregulation, 
stimulation, evaluation and early initiation of breastfeeding, focused on the first 
minute of life in countries and areas with limited economic resources, We pretended
to determine the impact of the implementation of this program on newborn mortality,
through a systematic review and meta-analysis.
Method: A systematic review and meta-analysis was performed. We included 
observational studies and clinical trials in electronic databases, that evaluated the 
impact of the implementation of the 'Helping Babies Breathe' program on neonatal 
mortality. Two independent reviewers conducted data extraction and the study quality 
assessment. A fixed-effect and random-effect models were used to evaluated 
heterogeneity, using Cochrane Q and I2
, and stratified analyses were performed by 
age and type of outcome, to determine the sources of heterogeneity.
Results: Most of the included studies were carried out in countries with low and low middle economic resources, by means of an educational strategy of training health 
personnel and / or midwives who attend the binomial neonate-mother at birth. A 
decrease in overall mortality was observed with an OR 0.67 (95%CI 0.57 - 0.80) and 
in intrapartum mortality with an OR 0.62 (95%CI 0.51 - 0.75). A high heterogeneity 
was found which was partly explained by differences in the gestational age of the 
participants.
Discussion and Conclusions: The implementation of the program "Helping Babies 
breathe", in countries with low and medium-low economic resources, have a
significative impact on reducing neonatal mortality, especially in intrapartum 
mortality.
%I Universidad de La Sabana
%T Impact of the helping babies breathe program on neonatal mortality and morbidity : Systematic review and meta-analysis
%~ Intellectum