%0 Journal Article
%A Carugati, Manuela
%A Aliberti, Stefano
%A Reyes, Luis Felipe
%A Sadud, Ricardo Franco
%A Irfan, Muhammad
%A Prat, Cristina
%A Soni, Nilam J.
%A Faverio, Paola
%A Gori, Andrea
%A Blasi, Francesco
%A Restrepo, Marcos I.
%8 2018-08-19
%@ 2312-0541
%U http://hdl.handle.net/10818/43695
%X This study aimed to describe real-life microbiological testing of adults hospitalised with community-acquired pneumonia (CAP) and to assess concordance with the 2007 Infectious Diseases Society of America (IDSA)/American Thoracic Society (ATS) and 2011 European Respiratory Society (ERS) CAP guidelines.

This was a cohort study based on the Global Initiative for Methicillin-resistant Staphylococcus aureus Pneumonia (GLIMP) database, which contains point-prevalence data on adults hospitalised with CAP across 54 countries during 2015.

In total, 3702 patients were included. Testing was performed in 3217 patients, and included blood culture (71.1%), sputum culture (61.8%), Legionella urinary antigen test (30.1%), pneumococcal urinary antigen test (30.0%), viral testing (14.9%), acute-phase serology (8.8%), bronchoalveolar lavage culture (8.4%) and pleural fluid culture (3.2%). A pathogen was detected in 1173 (36.5%) patients. Testing attitudes varied significantly according to geography and disease severity. Testing was concordant with IDSA/ATS and ERS guidelines in 16.7% and 23.9% of patients, respectively. IDSA/ATS concordance was higher in Europe than in North America (21.5% versus 9.8%; p<0.01), while ERS concordance was higher in North America than in Europe (33.5% versus 19.5%; p<0.01).

Testing practices of adults hospitalised with CAP varied significantly by geography and disease severity. There was a wide discordance between real-life testing practices and IDSA/ATS/ERS guideline recommendations.
%I European Respiratory Journal Open Research
%K Pneumonia
%K Microbiological
%K Diagnostic testing
%K Patients
%T Microbiological testing of adults hospitalised with community-acquired pneumonia: an international study
%R 10.1183/23120541.00096-2018
%~ Intellectum