%0 Generic
%A Betancur, Luz A.
%A Naranjo Gaybor, Sandra J.
%A Vinchira Villarraga, Diana M.
%A Moreno Sarmiento, Nubia C.
%A Maldonado, Luis A.
%A Suarez Moreno, Zulma R.
%A Acosta González, Alejandro
%A Padilla Gonzalez, Gillermo F.
%A Puyana, Mónica
%A Castellanos, Leonardo
%A Ramos, Freddy A.
%8 2017
%U http://hdl.handle.net/10818/35369
%X Marine bacteria are considered as promising sources for the discovery of novel biologically
active compounds. In this study, samples of sediment, invertebrate and algae were collected from the Providencia and Santa Catalina coral reef (Colombian Caribbean Sea) with
the aim of isolating Actinobateria-like strain able to produce antimicrobial and quorum
quenching compounds against pathogens. Several approaches were used to select actinobacterial isolates, obtaining 203 strains from all samples. According to their 16S rRNA gene
sequencing, a total of 24 strains was classified within Actinobacteria represented by three
genera: Streptomyces, Micromonospora, and Gordonia. In order to assess their metabolic
profiles, the actinobacterial strains were grown in liquid cultures, and LC-MS-based analyses from ethyl acetate fractions were performed. Based on taxonomical classification,
screening information of activity against phytopathogenic strains and quorum quenching
activity, as well as metabolic profiling, six out of the 24 isolates were selected for follow-up
with chemical isolation and structure identification analyses of putative metabolites involved
in antimicrobial activities.
%I PLoS ONE
%K Bacterias marinas
%K Actinobacteria
%K Streptomyces
%K Micromonospora
%T Marine Actinobacteria as a source of compounds for phytopathogen control: An integrative metabolic-profiling / bioactivity and taxonomical approach
%~ Intellectum