%0 Journal Article
%A García Casallas, Julio César
%A Villalobos Monsalve, Walter
%A Arias Villate, Sara Consuelo
%A Fino Solano, Ingrid Marisol
%8 2018
%@ 1752-1947
%U http://hdl.handle.net/10818/34929
%X Background: Brucellosis is one of the most widespread zoonoses worldwide. It can affect any organ system, particularly
the gastrointestinal system, but there is no report of acute liver failure as a brucellosis complication.
Case presentation: We present a case of acute liver failure secondary to brucellosis infection. A 75-year-old Hispanic
man presented to a University Hospital in Chía, Colombia, with a complaint of 15 days of fatigue, weakness, decreased
appetite, epigastric abdominal pain, jaundice, and 10 kg weight loss. On examination in an emergency room, abdomen
palpation was normal with hepatosplenomegaly and the results of a liver function test were elevated. The diagnosis of
brucellosis was confirmed by epidemiological contact and positive Rose Bengal agglutination with negative enzyme-linked
immunosorbent assay immunoglobulin M for Brucella. He was then treated with doxycycline plus trimethoprim/
sulfamethoxazole, with a favorable clinical outcome.
Conclusions: The clinical presentation of brucellosis can be very imprecise because it can affect any organ system;
however, there is no report of acute liver failure as a brucellosis complication. This is the first reported case in the
Colombian literature of acute liver failure due to brucellosis. We found this case to be of interest because it could
be taken into account for diagnosis in future appearances and we described adequate treatment and actions to
be taken at presentation
%I Journal of Medical Case Reports
%K Brucellosis
%K Acute liver failure
%K Zoonosis
%K Parasitic infections
%T Acute liver failure complication of brucellosis infection: a case report and review of the literature
%~ Intellectum