%0 Generic
%A Arias Acosta, Catalina
%8 2014-11-14
%U http://hdl.handle.net/10818/12469
%X Introducción: El síndrome de apnea obstructiva del sueño se cataloga como un problema  de salud pública, debido a su alta prevalencia la cual se sitúa entre un 2% a 26 %, en la población en general  , con el agravante que es sub -diagnosticada al no existir métodos  de tamizaje suficientemente válidos y fiables, es así como los métodos existentes se han  basado en cuestionarios o modelos clínicos que cuantifican la presencia de síntomas  clínicos, dentro de los más difundidos esta la escala de Epworth que valora la  somnolencia diurna, el cuestionario de Berlín que identifica los paciente con sospecha de  SAOS en atención primaria y la escala de NAMES producto de la construcción de un  modelo a partir de los síntomas clínicos y medidas antropométricas.
%X Introduction: Obstructive sleep apnea had classified as a public health problem due to
 its high prevalence, which is between 2% to 26% of the general population 1. The other
way, the absence methods sufficiently valid and reliable screening produce sub -
 diagnostic. There is methods that based on questionnaires or clinical models that quantify
 the presence of clinical symptoms. The most widespread is the Epworth scale that
 assesses daytime sleepiness, the Berlin questionnaire identifies the patient with suspected
 OSA in primary care and the scale of product NAMES building a model based, clinical
 symptoms and anthropometric measurements.
 Objective: To develop a scale in the prediction of OSA, it based on clinical and
 anthropometric characteristics in a population of patients with clinical suspicion of OSA.
 Methods: A cross-sectional observational study was conducted adult subjects referred for
 clinical suspicion of OSA who underwent overnight polysomnographic study, diagnosis
 of OSA is made from hiccupped apnea index (AHI) was included> 5 events / hour.
 Variables that were associated with the presence of OSA, and who had a biological
 plausibility were included in the building of the model.
 Yielding six models by the method of Stepwise Forward, the most parsimonious model
 included the variables age, sex, BMI, neck circumference and snoring, the scale scores
 were assigned considering the OR values obtained from each of the variables, this was
 validated from the point of view of discrimination and calibration in a new population.
 Results: Among 2553 subjects with OSAS prevalence of 91.4% was found while in 1386
 the population of subjects where the scale was validated, the prevalence was 96.2%, the
 variables associated with the presentation of OSAS were: neck circumference, BMI,
 presence or absence of snoring, age and sex, no statistically significant association with
 the Epworth scale found. The scale showed adequate discrimination ability with area
 under the ROC curve of 0.76 (95% CI 0.67 to 0.83) and a proper calibration for a given
value of �ℎ�!  = 27.2 p< 0.001 in the Hosmer-Lemeshow test.
 Conclusions: The present scale showed adequate discriminatory and calibration capacity
 of predict the occurrence of OSA in this population. However due to the high prevalence
 of OSAS, the predictive power is high even with scores of 0, being within a range  probabilities between 0.89 to 0.99, it is important to validate this scale in a population
 whose prevalence of OSA is less in order to evaluate the discrimination ability.
%K Apnea -- Enfermedades -- Colombia
%K Sueño -- Enfermedades -- Colombia
%K Diagnóstico -- Enfermedades -- Sueño
%T Construcción y validación de una escala que determine la presencia de síndrome de apnea obstructiva del sueño en pacientes con sospecha clínica basada en medidas antropométricas y síntomas clínicos.
%~ Intellectum