@misc{10818/64208,
year = {2017},
month = {10},
url = {http://hdl.handle.net/10818/64208},
abstract = {Objective: To investigate the role of HLA-B and HLA-DR genes as contributors to genetic susceptibility and clinical expression of the spondyloarthropathies (SpA) in the Mexican population.  Methods: The study included 172 patients with SpA (undifferentiated SpA 83, ankylosing spondylitis (AS) 64, and reactive arthritis 25) and 99 healthy controls. The HLA-B and HLA-DR alleles were detected by the polymerase chain reaction with sequence-specific primers technique. Patient assessment included demographic data, diagnostic categories, and disease patterns. Statistical methods included the Mantel-Haenzel χ2 test, Fisher's exact test, and Woolf method for odds ratio (OR). Differences of continuous variables between HLA allele groups were calculated by Student's t test.},
publisher = {Anales de las Enfermedades Reumáticas},
title = {Effect of HLA-B and HLA-DR genes on susceptibility to and severity of spondyloarthropathies in Mexican patients},
title = {Efecto de los genes HLA-B y HLA-DR sobre la susceptibilidad y severidad de las espondiloartropatías en pacientes mexicanos},
doi = {10.1136/ard.61.8.714},
author = {Vargas Alarcón, G. and Londoño, JD and Hernández Pacheco, G. and Burgos-Vargas,  R.},
}