%0 Generic
%A Sanabria, Álvaro
%A Domínguez, Luis C.
%A Vega, Valentín
%A Osorio, Camilo
%A Duarte, Daniel
%8 2011-10-25
%@ 0124-0064
%U http://hdl.handle.net/10818/49636
%X Objective Hypocalcaemia is a frequently arising complication following total
thyroidectomy. Routine postoperative prophylactic administration of vitamin D or
metabolites and calcium reduce the incidence of symptomatic hypocalcaemia; this
article reports evaluating its cost-effectiveness in Colombia.
Methods Meta-analysis was used for comparing the administration of vitamin D or
metabolites to oral calcium or no treatment at all in patients following total thyroidectomy
and a cost-effectiveness analysis was designed based on a decision-tree model with
local costs.
Results The OR value for the comparison between calcitriol and calcium compared to
no treatment and to exclusive calcium treatment groups was 0.32 (0.13-0.79 95 %CI)
and 0.31 (0.14-0.70 95 %CI), respectively. The most cost-effective strategy was vitamin
D or metabolites and calcium administration, having a US $0.05 incremental costeffectiveness ratio.
Conclusion Prophylactic treatment of hypocalcaemia with vitamin D or metabolites +
calcium or calcium alone is a cost-effective strategy
%I Revista de salud Publica
%T Cost-effectiveness analysis regarding
postoperative administration of vitamin-D
and calcium after thyroidectomy to
prevent hypocalcaemia
%T Análisis de costo-efectividad de la administración postoperatoria de
Vitamina D y calcio después de tiroidectomía para la prevención de la
hipo calcemia
%~ Intellectum